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INHALEIndividualized Nutrition to Help Asthmatics Improve Lung Function and Energetics (INHALE)

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What is being tested

DGA Diet

+ MCT Diet

+ KETO Diet

Other
Who is being recruted

Acid-Base Imbalance+11

+ Acidosis

+ Asthma

From 18 to 65 Years
+13 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: July 2024
See protocol details

Summary

Principal SponsorPennington Biomedical Research Center
Study ContactJacob T Mey, PhD, RDMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: July 17, 2024

Actual date on which the first participant was enrolled.

The study aims to explore how different diets can affect people with asthma, specifically focusing on improving lung function and energy levels. It targets adults living with asthma, a condition that causes breathing difficulties and can significantly impact daily life. The researchers hope to determine if certain dietary changes can help manage asthma symptoms better and possibly identify factors that predict how well individuals respond to these dietary interventions. This research is important as it could offer new, non-medicinal ways to improve asthma management. Participants in this trial will first go through a screening and preparation period. They will then follow three different diets, each lasting seven days, with a break of at least seven days in between each one to ensure no carry-over effects. During the study, the researchers will assess asthma control and lung function after each diet to see which type of diet has the most beneficial impact. The process involves careful monitoring to evaluate how each dietary change influences asthma symptoms and lung performance.

Official TitleIndividualized Nutrition to Help Asthmatics Improve Lung Function and Energetics (INHALE)
NCT06151405
Principal SponsorPennington Biomedical Research Center
Study ContactJacob T Mey, PhD, RDMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

15 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Acid-Base ImbalanceAcidosisAsthmaBronchial DiseasesHypersensitivityHypersensitivity, ImmediateImmune System DiseasesKetosisLung DiseasesLung Diseases, ObstructiveMetabolic DiseasesNutritional and Metabolic DiseasesRespiratory HypersensitivityRespiratory Tract Diseases

Criteria

6 inclusion criteria required to participate
Age: 18-65 years

BMI: 18.5 - 29.99 kg/m2

asthma diagnosed by medical specialist (confirmed in medical history)

partly controlled or uncontrolled asthma by Asthma Control Test score ≤22

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7 exclusion criteria prevent from participating
Diabetes or using diabetes medications that may lower blood glucose levels

point of care fasting blood glucose ≥126 mg/dl or triglycerides ≥400 mg/dl

current smoking or smoking history of greater than 10 pack-years

other significant respiratory or cardiac disease or the presence of clinically important comorbidities, e.g., COPD, renal failure, liver disease; uncontrolled hypertension defined as systolic blood pressure ≥160 mm/Hg, or diastolic blood pressure ≥100 mm/Hg

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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

3 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
7 days of a diet consistent with the Dietary Guidelines for Americans (DGA).

Group II

Experimental
7 days of a diet consistent with the Dietary Guidelines for Americans supplemented with medium chain triglycerides (MCT).

Group III

Experimental
7 days of a ketogenic diet (KETO).

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Pennington Biomedical Research Center

Baton Rouge, United StatesOpen Pennington Biomedical Research Center in Google Maps
Recruiting
One Study Center