Impact of Fermented Pulses on Inflammation and the Gut Microbiota
Unfermented chickpea
+ Fermented chickpea
Inflammation
+ Pathologic Processes
+ Pathological Conditions, Signs and Symptoms
Basic Science Study
Summary
Study start date: September 1, 2025
Actual date on which the first participant was enrolled.This study focuses on understanding how eating fermented pulses, like chickpeas, can affect inflammation and gut health. Fermentation is believed to help increase the production of butyrate, a beneficial compound produced by gut bacteria. Butyrate is important because it can help reduce inflammation in the body. By comparing the effects of fermented versus unfermented chickpeas, this study aims to determine if fermented pulses can lead to better health outcomes by lowering inflammation. This research is particularly important as it may offer a simple dietary change to help manage inflammation-related conditions. Participants in this study will eat meals containing either fermented or unfermented chickpeas daily. After a set period, they will switch to the other type of chickpeas, with a break in between to clear the effects of the first type. This approach, known as a cross-over design, allows the researchers to directly compare the effects of each diet on the same individuals. The study will measure changes in markers of inflammation and levels of butyrate to evaluate the impact of the fermented pulses. The goal is to see if the fermented pulses lead to a decrease in inflammation by boosting the production of beneficial substances in the gut.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.30 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Basic Science Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 65 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives