Recruiting soon

Impact of Fermented Pulses on Inflammation and the Gut Microbiota

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Unfermented chickpea

+ Fermented chickpea

Other
Who is being recruted

Inflammation

+ Pathologic Processes

+ Pathological Conditions, Signs and Symptoms

From 18 to 65 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Basic Science Study

Interventional
Study Start: September 2025
See protocol details

Summary

Principal SponsorPenn State University
Study ContactDarrell W Cockburn, PhDMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: September 1, 2025

Actual date on which the first participant was enrolled.

This study focuses on understanding how eating fermented pulses, like chickpeas, can affect inflammation and gut health. Fermentation is believed to help increase the production of butyrate, a beneficial compound produced by gut bacteria. Butyrate is important because it can help reduce inflammation in the body. By comparing the effects of fermented versus unfermented chickpeas, this study aims to determine if fermented pulses can lead to better health outcomes by lowering inflammation. This research is particularly important as it may offer a simple dietary change to help manage inflammation-related conditions. Participants in this study will eat meals containing either fermented or unfermented chickpeas daily. After a set period, they will switch to the other type of chickpeas, with a break in between to clear the effects of the first type. This approach, known as a cross-over design, allows the researchers to directly compare the effects of each diet on the same individuals. The study will measure changes in markers of inflammation and levels of butyrate to evaluate the impact of the fermented pulses. The goal is to see if the fermented pulses lead to a decrease in inflammation by boosting the production of beneficial substances in the gut.

Official TitleImpact of Fermented Pulses on Inflammation and the Gut Microbiota
NCT06134076
Principal SponsorPenn State University
Study ContactDarrell W Cockburn, PhDMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

30 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

InflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Criteria

1 inclusion criteria required to participate
Healthy adults

5 exclusion criteria prevent from participating
Taken antibiotics within the past month

Taking any medication for the management of diabetes or obesity

Are pregnant

BMI > 24.9

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental

Group II

Experimental

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
This study has no location dataSave this study to your profile to know when the location data is available.
Recruiting soonNo study centers
Impact of Fermented Pulses on Inflammation and the Gut Microbiota | PatLynk