PEDD-UFEPain Reduction and Ovarian Perfusion Following Uterine Fibroid Embolization Via Pressure-Enabled Drug Delivery With the TriNav Infusion System (PEDD-UFE)

Uterine fibroids are non-cancerous growths that frequently occur in women of childbearing age. They can cause symptoms such as heavy menstrual bleeding, pain, and sometimes affect fertility, impacting overall quality of life. This study aims to improve treatment for women who want to keep their uterus and find relief beyond what standard medical treatments provide. The focus is on using a technique called Pressure-Enabled Drug Delivery during a procedure known as uterine fibroid embolization (UFE). The study's goal is to see if this method can better manage fibroid symptoms and improve life quality for these women. Participants in this study undergo uterine fibroid embolization, a minimally invasive procedure where blood flow to the fibroids is blocked to shrink them. The study uses a specific drug delivery system, the TriNav Infusion System, to administer treatment directly to the fibroids. Researchers will evaluate how well this approach reduces pain and improves blood flow to the ovaries. The study seeks to determine the effectiveness and safety of this targeted treatment method, aiming to offer a better alternative for fibroid management.