The Efficacy of Babaodan Capsules in Preventing Radiation Pneumonitis in Locally Advanced Non-Small Cell Lung Cancer Patients: A Phase II Clinical Trial

This clinical trial is focused on finding out if Babaodan (BBD) capsules can help prevent lung problems, specifically radiation pneumonia, in patients with locally advanced non-small cell lung cancer who are receiving radiation therapy. Radiation therapy can cause lung injury, which happens in two stages: early-stage inflammation known as radiation pneumonia, and later-stage lung scarring called pulmonary fibrosis. These lung issues are caused by the body's reaction to radiation, which can damage cells and lead to inflammation. By studying the effects of BBD, which is known to have anti-inflammatory properties, the trial aims to discover if it can reduce the risk of these lung complications and improve the treatment outcomes for these cancer patients. Participants in this study will take BBD capsules while they receive their standard cancer treatment, which includes both chemotherapy and radiation therapy. The BBD capsules are taken orally and are given during and after the radiation treatment. Researchers will observe the patients to see if BBD helps in reducing the symptoms of radiation pneumonia and if it affects the overall health of the patients by minimizing side effects. The study aims to measure the incidence and severity of lung problems during and after the treatment period to see if BBD offers a protective effect against radiation-induced lung damage.