Effect of Subarachnoid Hyperbaric Bupivacaine on Mean Arterial Pressure in Obese Pregnant Patients Undergoing Cesarean Section
5mg bupivacaine
+ 10mg bupivacaine
Body Weight+5
+ Nutrition Disorders
+ Nutritional and Metabolic Diseases
Supportive Care Study
Summary
Study start date: August 1, 2023
Actual date on which the first participant was enrolled.This clinical trial is investigating how a specific anesthetic called subarachnoid hyperbaric bupivacaine affects blood pressure in obese pregnant women who are undergoing a C-section. The trial focuses on women who are at least 37 weeks pregnant, have a BMI of 30 or above, and have babies that are doing well. This research is important because keeping blood pressure stable during surgery is crucial for the safety of both the mother and the baby. Understanding the effects of this anesthetic could improve the care provided during cesarean sections for obese patients. In the study, participants receive anesthesia through a mixed technique that involves both epidural and subarachnoid blocks. The procedure begins with a thorough pre-anesthetic evaluation and monitoring of vital signs. Patients are randomly assigned to receive different doses of the anesthetic, either 5 mg or 10 mg, to observe its effect on mean arterial pressure (MAP). The researchers monitor vital signs frequently during surgery and assess sensory and motor blockades. They also record nausea and vomiting incidents, and evaluate the newborn's condition using the Apgar score. Data collected will help determine if the anesthetic dose affects blood pressure and overall surgical outcomes, providing insights into safer anesthetic practices for obese pregnant patients.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.106 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Supportive Care Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Female
Biological sex of participants that are eligible to enroll.From 18 to 45 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
ExperimentalStudy Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location