Completed

Risk Education Technology As Individualized Neuroprotection

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What is being tested

Brain Health Education

+ Alzheimer Disease Education

Behavioral
Who is being recruted

Alzheimer Disease+6

+ Mental Disorders

+ Brain Diseases

From 53 to 105 Years
+16 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Interventional
Study Start: December 2023
See protocol details

Summary

Principal SponsorRetain Health, Inc
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: December 7, 2023

Actual date on which the first participant was enrolled.

Alzheimer's disease is a growing health concern with limited treatment options. It often starts affecting the brain long before any memory problems appear. This study focuses on using mobile technology to help people identify their personal risk factors for Alzheimer's and monitor their memory and cognitive abilities over time. By using a phone-based app, the study aims to make it easier and more affordable for people, especially those with a family history of Alzheimer's, to access important information and tools that can help prevent or delay dementia. The app uses methods like online education and text messaging, which have been successful in reducing risks for other chronic diseases, to educate users about Alzheimer's. Participants in the study will use a cell phone application to receive personalized monitoring and education. They will begin by visiting a study website to see if they qualify and, if eligible, they will complete some initial assessments and memory tests online. After signing an electronic consent form, participants will be divided randomly into two groups, each using different educational strategies about Alzheimer's risk. Researchers will follow participants for six months, using text messages to keep participants engaged and track their progress, to compare the effectiveness of these strategies in protecting brain health and possibly reducing the risk of Alzheimer's.

Official TitleRisk Education Technology As Individualized Neuroprotection
NCT06027320
Principal SponsorRetain Health, Inc
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

992 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 53 to 105 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Alzheimer DiseaseMental DisordersBrain DiseasesCentral Nervous System DiseasesDementiaNervous System DiseasesNeurodegenerative DiseasesNeurocognitive DisordersTauopathies

Criteria

4 inclusion criteria required to participate
be at least 53 years of age
have a family history of Alzheimer's Disease (AD)
have a compatible phone/device (phone allowing text messages and with internet access, and/or tablet device with the same capabilities)
a minimum of one of the following risk factors: body mass index (BMI) of < 25 kg/m2, history of pre-diabetes/diabetes, high blood pressure, high cholesterol, smoking, low physical activity, low fish intake (< 3 times per month), high alcohol intake (< 7 servings per week for a women and <14 servings a week for men), diagnosed with mild or moderate depression.
12 exclusion criteria prevent from participating
have a diagnosis of dementia due to AD
other dementia
women who are currently pregnant or who plan on becoming pregnant in the next 6 months
BMI <18.5 kg/m2
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Subjects will receive an Alzheimer's risk assessment, memory testing, and brain health education, in addition to text message communication.

Group II

Subjects will receive an Alzheimer's risk assessment, memory testing, and general education about Alzheimer's disease, in addition to text message communication.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Retain Health, Inc.

Bedford, United StatesOpen Retain Health, Inc. in Google Maps
CompletedOne Study Center