Recruiting

The Effects of Snus on Home Blood Pressure and Metabolism

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What is being tested

Snus with or without tobacco

Other
Who is being recruted

Body Weight+8

+ Metabolic Diseases

+ Nutrition Disorders

From 18 to 50 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Interventional
Study Start: October 2023
See protocol details

Summary

Principal SponsorUniversity Hospital, Linkoeping
Study ContactPeder af Geijerstam, MD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 9, 2023

Actual date on which the first participant was enrolled.

This study explores how the use of snus, a form of smokeless tobacco placed under the lip, affects blood pressure and metabolism over time. It focuses on individuals who regularly used snus and then stopped. The study seeks to understand how resuming snus consumption might impact their blood pressure and metabolic health. By observing these changes, researchers aim to gain insights into the cardiovascular risks associated with snus, especially since it is less studied compared to smoking. This information could help in understanding the broader health implications of snus use, particularly its effect on long-term heart health. Participants in this study include 28 healthy adults who initially used snus daily. These participants will quit snus for three months, during which their blood pressure and various metabolic markers like cholesterol and blood sugar levels will be monitored. If any participants return to using snus during the study, these health metrics will continue to be tracked for another three months. Daily blood pressure recordings and reports of snus usage will be collected. Participants will undergo specific health checks at the start and during the study to evaluate changes in weight and blood components such as glucose and cholesterol. They will receive compensation for their participation, and all procedures will follow ethical guidelines to ensure safety and informed consent.

Official TitleThe Effects of Snus on Home Blood Pressure and Metabolism
NCT06019910
Principal SponsorUniversity Hospital, Linkoeping
Study ContactPeder af Geijerstam, MD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

28 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Body WeightMetabolic DiseasesNutrition DisordersNutritional and Metabolic DiseasesObesitySigns and SymptomsPathological Conditions, Signs and SymptomsOvernutritionDyslipidemiasOverweightLipid Metabolism Disorders

Criteria

2 inclusion criteria required to participate
daily use (defined as at least once daily for at least 1 month) o snus

the ability to use online questionnaires written and answered in Swedish

5 exclusion criteria prevent from participating
simultaneous use of any other nicotine or tobacco product (including cigarette smoking, e-cigarettes, and nicotine replacement therapy)

drug use (including cannabis)

alcohol dependence

known cardiovascular disease (including hypertension, previous myocardial infarction, stroke, peripheral arterial disease, or angina pectoris), kidney disease, hormonal disease (including diabetes mellitus) or eating disorder

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Snus cessation followed by potential snus relapse

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Primary Health Care Center Cityhälsan Centrum

Norrköping, SwedenOpen Primary Health Care Center Cityhälsan Centrum in Google Maps
Recruiting
One Study Center
The Effects of Snus on Home Blood Pressure and Metabolism | PatLynk