Completed

A Single Group Clinical Trial to Examine the Effects of a Daily Supplement on Common Symptoms of Perimenopause and Menopause

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What is being tested

Daily Balance Gummy

Dietary Supplement
Who is being recruted

From 40 to 65 Years
See all eligibility criteria
How is the trial designed

Other Study

Interventional
Study Start: August 2023
See protocol details

Summary

Principal SponsorHologram Sciences
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 14, 2023

Actual date on which the first participant was enrolled.

This clinical trial is focused on exploring the potential benefits of a daily supplement to help women experiencing perimenopause and menopause. The study aims to see if taking Hologram Sciences' Daily Balance Gummy Supplements can lessen common symptoms such as hot flashes, night sweats, mood swings, anxiety, fatigue, and brain fog. These symptoms can greatly impact daily life, and finding an effective way to manage them could improve the overall well-being of many women going through these natural life stages. Participants in the study will take these gummy supplements every day for a total of 12 weeks. Throughout the study, they will be asked to fill out questionnaires at the beginning, and then again at weeks 4, 8, and 12, to track any changes in their symptoms. At the end of the study, participants will also count the remaining gummies in their jar, which helps researchers understand how consistently the gummies were taken. This approach allows the researchers to gather detailed feedback on the supplement's effectiveness in managing menopause-related symptoms.

Official TitleA Single Group Clinical Trial to Examine the Effects of a Daily Supplement on Common Symptoms of Perimenopause and Menopause
Principal SponsorHologram Sciences
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

40 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Other Study

Some studies explore topics that don't fall into a specific category. These might include innovative research, new technologies, or emerging healthcare areas.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Female

Biological sex of participants that are eligible to enroll.

From 40 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

Inclusion Criteria: Women aged 40-65 years old Must be experiencing at least two symptoms of menopause, such as sleep disturbances, mood changes, fatigue and lack of energy, changes in sexual function, urinary changes, irregular or absent periods, or vaginal changes Must experience hot flashes and/or night sweats at least 5 times per day Can be either natural or surgical menopause (or perimenopause) Willing to adhere to the study protocol for the duration of the study Willing to consult with their physician prior to starting the trial if taking any of the following medications: Levothyroxine Liothyronine Calcipotriene (Dovonex) Digoxin (Lanoxin) Diltiazem (Cardizem) Verapamil (Calan, others) Thiazide diuretics Atorvastatin (Lipitor) Warfarin - Might increase the amount of time it takes for blood clotting. Minosalicylic acid (Paser) Colchicine (Colcrys, Mitigare, Gloperba) Metformin (Glumetza, Fortamet, others) Proton pump inhibitors (omeprazole (Prilosec), lansoprazole (Prevacid) or other stomach acid-reducing drugs) Phenytoin (Dilantin) Antihypertensive drugs Phenobarbital (Luminal) Amiodarone (Cordarone) Levodopa Exclusion Criteria: Not experiencing hot flashes and/or night sweats at least 5 times per day Has taken herbal supplements or multivitamins within the last 1 month Current use of conventional hormone replacement therapies, or plan to start during the study duration Current use of hormonal birth control, or plan to start during the study duration Known allergies to any product ingredients including the purified isoflavone genistein History of uterine fibroids, endometriosis, polycystic ovarian syndrome, or history of abnormal pap smear Anyone with any known severe allergies requiring the use of an epi-pen Unwilling to adhere to the study protocol Anyone living with uncontrolled or chronic health disorders, including oncological or psychiatric disorders No planned invasive medical procedures for the duration of the study Pregnant or breastfeeding

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
One Daily Balance Gummy should be taken with the last meal of the day.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Citruslabs

Santa Monica, United StatesOpen Citruslabs in Google Maps
CompletedOne Study Center