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MSImpact of Adding Cognitive Behaviour Therapy to Supervised Pilates-based Core Stability Training on Balance and Walking in Patients With Multiple Sclerosis

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What is being tested

pilates based core stability training and congnitive therapy

+ Pilates based core stability training

Other
Who is being recruted

Autoimmune Diseases+4

+ Demyelinating Diseases

+ Immune System Diseases

From 18 to 70 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: August 2023
See protocol details

Summary

Principal SponsorCairo University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 15, 2023

Actual date on which the first participant was enrolled.

This study focuses on helping people with Multiple Sclerosis (MS) improve their balance and walking abilities. MS often leads to muscle weakness and trouble with balance due to nerve damage in the central nervous system. This can significantly affect a person's quality of life, making daily activities challenging. The study aims to see if adding Cognitive Behavioral Therapy (CBT) to Pilates-based core stability training can offer better improvements in balance and walking than Pilates alone. This is important because improving core stability might lead to better control over body movements and reduce symptoms like fatigue, which is common in MS. Participants in the study are divided into two groups. One group will receive both Cognitive Behavioral Therapy and Pilates exercises, while the other group will only do the Pilates exercises. The Pilates exercises focus on strengthening core muscles, which are crucial for maintaining stability and proper posture. The treatment lasts for eight weeks, and researchers will observe how well each approach helps with balance and walking. By comparing the two groups, the study aims to determine whether the combination of therapies offers more benefits, potentially leading to better treatment strategies for people with MS.

Official TitleImpact of Adding Cognitive Behaviour Therapy to Supervised Pilates-based Core Stability Training on Balance and Walking in Patients With Multiple Sclerosis
NCT05993819
Principal SponsorCairo University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

50 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 70 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Autoimmune DiseasesDemyelinating DiseasesImmune System DiseasesMultiple SclerosisNervous System DiseasesAutoimmune Diseases of the Nervous SystemDemyelinating Autoimmune Diseases, CNS

Criteria

Inclusion Criteria: * A score of 3.5 or less on the Expanded Disability Status Scale (EDSS) because individuals with an EDSS score greater than 3.5 need more assistance, being less independent. * Age over 18 years * All definite multiple sclerosis patients diagnosed as MS according to revised McDonald criteria 2017 * Both males and females were included Exclusion Criteria: -Individuals who had orthopedic, neurologic, and psychological problems that accompanied MS that might affect the treatment results- * serious cognitive problems; performed regular exercise; were involved in another physiotherapy and rehabilitation program related to MS(Kurtzke, 1993) * Pregnant were not included. * Individuals who had an exacerbation during the treatment period

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
the patients will receive pilates and cognitive therapy three times a week for eight weeks

Group II

Active Comparator
the patients will receive pilates three times a week for eight weeks

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.
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