Comparison of the Clinical Effectiveness of Calcium Silicate-based Sealer and Epoxy Resin-based Sealer in Single-visit Root Canal Treatment
Epoxy resin-based sealers (ERS)
+ Calcium silicate-based sealers (CSS)
Neurologic Manifestations+4
+ Pain
+ Pain, Postoperative
Treatment Study
Summary
Study start date: June 1, 2020
Actual date on which the first participant was enrolled.Background: Sealers have been concerned with obturation. However, studies for assessing the effectiveness of endodontic treatment of sealer based on Calcium Silicate have been not much. Objective: This study aimed to assess the effectiveness of endodontic treatment of sealer based on Calcium Silicate Methods: A prospective, single-blind, clinical trial was conducted from June 2020 to December 2020 with 42 irreversible pulpitis teeth by one clinician. The postoperative pain was assessed after root canal treatment using sealer based on Calcium Silicate and sealer based on Epoxy resin after 6 hours, 12 hours, 24 hours, 48 hours, 72 hours and 7 days and inconvenient symptoms were assessed after 7 days, 3 months and 6 months. t-test, Mann-Whitney and Wilcoxon analysis were applied. Key words: obturation, sealer based on Calcium Silicate and sealer based on Epoxy resin
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.42 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: * aged 18 years or older * teeth diagnosed with irreversible pulpitis by electrical and thermal tests (+) * had clinical symptoms like continuous or spontaneous pain, teeth exposed to sudden temperature changes, especially cold stimuli, causing sharp pain and persisting after stimulus removal * these teeth must have healthy periodontal tissue and sufficient clinical teeth crown for isolation with a rubber dam Exclusion criteria: Patients with: * Pregnant * Have a systemic disease requiring antibiotics or have an allergic reaction * Have maxillofacial pathology, cellulitis, occlusal trauma, and temporomandibular disorders, have endodontic periodontal lesions, periodontal abscesses * Have taken a previous pain reliever within 24 hours Tooth: * Roots internally or externally resorbed, cracked or broken * Have had failed endodontic treatment, or the root canal cannot be controlled for leakage * No opposing teeth
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
Active ComparatorGroup II
Active ComparatorStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
University of Medicine and Pharmacy at Ho Chi Minh City
Ho Chi Minh City, VietnamOpen University of Medicine and Pharmacy at Ho Chi Minh City in Google Maps