Completed

Periodontal Status and Cardio Ankle Vascular Index Relationship in Short-term Type 2 Diabetic Patients

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
Study Aim

This study aims to observe the relationship between periodontal status and Cardio Ankle Vascular Index (CAVI) in individuals who have been recently diagnosed with type 2 diabetes, focusing on measuring average CAVI values in each study group.

What is being collected

Data Collection

Collected at a single point in time - Cross-sectional
Who is being recruted

Cardiovascular Diseases+12

+ Coronary Disease

+ Diabetes Mellitus

From 20 to 70 Years
+10 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Other

Utilizing specific methods not covered by standard models in order to address unique research questions.
Observational
Study Start: June 2022
See protocol details

Summary

Principal SponsorPamukkale University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: June 10, 2022

Actual date on which the first participant was enrolled.

This study focuses on understanding the connection between gum health and a measure of heart health called the Cardio Ankle Vascular Index (CAVI) in people who have had type 2 diabetes for less than 5 years, as well as in generally healthy individuals. Both groups may or may not have severe gum disease, known as periodontitis. The research aims to provide insights into how gum health might be linked to heart health in these populations, potentially paving the way for improved care and management strategies for individuals with type 2 diabetes and severe periodontitis. Participants in this observational study will have their gum health assessed using the Classification of Periodontal and Peri-Implant Diseases and Conditions. Their heart health will be evaluated using the CAVI index, with higher values indicating poorer heart health. Various other health measures, such as body mass index, waist circumference, blood sugar levels, and blood pressure, will also be collected. The primary outcome of the study is to compare the mean CAVI values among the different study groups. The data collected will be analyzed using statistical software, with the aim of identifying any significant relationships between gum health and heart health.

Official TitleRelationship Between Periodontal Status and Cardio Ankle Vascular Index in Short-term Type 2 Diabetic or Systemically Healthy Patients With or Without Severe Periodontitis
NCT05866497
Principal SponsorPamukkale University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

136 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Other

Some studies use unique or mixed approaches that don't fit standard categories. These may include innovative observational methods or studies tailored to specific research questions.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 20 to 70 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Cardiovascular DiseasesCoronary DiseaseDiabetes MellitusDiabetes Mellitus, Type 2Endocrine System DiseasesHeart DiseasesMetabolic DiseasesStomatognathic DiseasesMouth DiseasesNutritional and Metabolic DiseasesPeriodontal DiseasesPeriodontitisVascular DiseasesMyocardial IschemiaGlucose Metabolism Disorders

Criteria

2 inclusion criteria required to participate
short-term type 2 diabetes mellitus diagnosis (<5 years) or systemically healthy subjects

patients with severe periodontitis or periodontally healthy subjects

8 exclusion criteria prevent from participating
had vascular diabetic complications

hypertensive and dyslipidaemic/hyperlipidaemic patients

Smokers and ex-smokers

pregnancy and lactation

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Pamukkale University Faculty of Dentistry

Denizli, Turkey (Türkiye)Open Pamukkale University Faculty of Dentistry in Google Maps
CompletedOne Study Center