Suspended

SEEearlySupported Employment and Education for Early Psychosis Recovery

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Individual Placement and Support (IPS)

Other
Who is being recruted

Mental Disorders+1

+ Psychotic Disorders

+ Schizophrenia

From 16 to 35 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: October 2022
See protocol details

Summary

Principal SponsorCharite University, Berlin, Germany
Study ContactAnna Willert, Dr. med.
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 18, 2022

Actual date on which the first participant was enrolled.

Psychotic disorders often develop a chronic course with devastating consequences for individuals, families, and societies usually with first onset during adolescence and early adulthood. Early intervention programs, which provide intensive, phase specific, psychosocial, and pharmacological treatment for people in the first five years after the initial psychotic episode (early psychosis) can significantly improve the outcome and are therefore strongly recommended in national and international guidelines. However, most early intervention programs in people with early psychosis still focus on improving symptoms and relapse prevention, rather than targeting educational and vocational recovery, although engagement in work and education is a high priority for young people with early psychosis and reduces the social disability associated with the disorder. The aim of the present study is to explore the effects of Supported Employment and Education (SEE) following the Individual Placement and Support (IPS) model in people with early psychosis. The investigators compare treatment as usual (TAU) in an outpatient psychiatric setting to TAU plus SEE.

Official TitleEnhancing Educational and Vocational Recovery in Adolescents and Young Adults With Early Psychosis Through Supported Employment and Education (SEE): A Randomized Controlled Trial. Acronym: SEEearly
NCT05824117
Principal SponsorCharite University, Berlin, Germany
Study ContactAnna Willert, Dr. med.
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

184 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 16 to 35 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Mental DisordersPsychotic DisordersSchizophreniaSchizophrenia Spectrum and Other Psychotic Disorders

Criteria

4 inclusion criteria required to participate
clinical diagnosis of early psychosis (DSM 5: schizophrenia spectrum and other psychotic disorders (297.1, 298.8, 295.4, 295.9, 295.7, 298.8, 298.9) within the last 5 years currently treated as outpatients

sufficient linguistic and intellectual abilities to take part in the study

interest in competitive employment or/and mainstream education

written informed consent

2 exclusion criteria prevent from participating
Learning disability or mental retardation as well as insufficient German language abilities (< A2)

physical or organic handicap that seriously impede work or educational functioning

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
The experimental intervention is treatment as usual (TAU) for adolescents and young adults with early psychosis in the respective recruitment centers for 12 months plus Supported Employment and Education following the Individual Placement and Support model.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 6 locations

Recruiting

Klinik für Sozialpsychiatrie, Zentrum für Psychiatrie Reichenau

Reichenau, GermanyOpen Klinik für Sozialpsychiatrie, Zentrum für Psychiatrie Reichenau in Google Maps
Recruiting

Klinik für Psychiatrie und Psychotherapie, LMU Klinikum

München, Germany
Recruiting

Klinik für Psychiatrie, Psychotherapie und Psychosomatik II, Günzburg

Ulm, Germany
Recruiting

Klinik für Psychiatrie und Psychotherapie Charité Campus Mitte

Berlin, Germany
Suspended6 Study Centers