Completed

Perturbation-induced Balance Training for Post-Stroke Individuals

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What is being tested

Balance training

Behavioral
Who is being recruted

Brain Diseases+4

+ Cardiovascular Diseases

+ Central Nervous System Diseases

From 21 to 80 Years
+8 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: January 2019
See protocol details

Summary

Principal SponsorNorthwestern University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 22, 2019

Actual date on which the first participant was enrolled.

This study focuses on improving balance in individuals who have experienced a stroke. It uses a unique method called perturbation-induced reactive standing balance training. This involves applying gentle, unexpected disturbances to help participants improve their balance reactions. The study is important because it aims to enhance the quality of life for stroke survivors by reducing the risk of falls and improving mobility. During the study, participants will wear a belt connected to a mechanical weight drop system. This system will apply small, sudden pulls to challenge their balance. Participants will be asked to respond naturally, using their more affected leg to maintain balance. The study will measure the frequency of using the affected leg for balance, the time it takes to initiate a step, and the ability to regain balance after a lean. These measurements will be taken before and after the training sessions. The training will consist of 6 sessions within a three-week period, each lasting about an hour. Safety measures, such as a harness and rest breaks, will be provided to ensure participants' well-being.

Official TitlePerturbation-induced Reactive Standing BalanceTraining in Persons Post Stroke
NCT05772936
Principal SponsorNorthwestern University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

13 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 21 to 80 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Brain DiseasesCardiovascular DiseasesCentral Nervous System DiseasesCerebrovascular DisordersNervous System DiseasesVascular DiseasesStroke

Criteria

3 inclusion criteria required to participate
at least 1 year post a single unilateral hemispheric stroke (CVA)

living independently in the community

able to walk 25 feet without assistive device

5 exclusion criteria prevent from participating
pain that limits movement

joint surgery of the lower extremity

unable to give consent

significant postural alignment deficits such as scoliosis or genu recurvatum

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
all enrolled subjects will participate in the perturbation-induced step training, 1 or 6 sessions about 1-1.5 hour (30-90 trials) each session.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Northwestern University

Chicago, United StatesOpen Northwestern University in Google Maps
CompletedOne Study Center