Completed

Auto-regulated Resistance-training for Improving Strength in Older Adults

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What is being tested

Resistance training

Behavioral
Who is being recruted

Atrophy+6

+ Muscular Atrophy

+ Nervous System Diseases

Over 50 Years
+2 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Interventional
Study Start: October 2022
See protocol details

Summary

Principal SponsorUniversity of Saskatchewan
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 15, 2022

Actual date on which the first participant was enrolled.

Auto-regulated resistance training has emerged as a resistance training paradigm to individualize programming; however, it remains to be elucidated whether auto-regulated resistance training provides a greater benefit than traditional standardized resistance training on physiological adaptations and performance outcomes in older adults. Traditional resistance training involves prescription of intensity as a percentage of the maximal amount of weight an individual can lift (for example, a resistance of 70% of maximal strength is a weight equal to 70% of the maximal weight a person can lift one time. An individual with this prescription would lift this weight for a number of repetitions to failure; i.e. usually 8-10 repetitions). Auto-regulation can be done two ways: "Subjective" auto-regulation involves lifting a weight for a number of repetitions until the individual reaches a certain "rating of perceived exertion". The rating of perceived exertion is on a scale of 1-10, with 10 being the most difficult or maximal exertion. For example, if one was prescribed a rating of perceived exertion of 8 they would lift a weight for a given number of repetitions until they believed they were at an 8/10 on the scale and had 2 repetitions left before failing. "Objective" auto-regulation involves lifting a weight for a given number of repetitions until a predetermined velocity of lifting is reached. For example, once someone starts to get fatigued while performing repeated lifting, the velocity of lifting will slow down. Once they have reached a critical slow velocity, the exercise would be stopped. There is some evidence that auto-regulation improves muscular strength to a greater extent than traditional resistance training in healthy populations. The research design is a prospective randomized trial comparing three training protocols in 30 participants. Participants will be randomized into one of three groups (n = 10 each), with matching on baseline strength: traditional standardized, subjective auto-regulated, and objective auto-regulated. Training will be twice per week for 12 weeks. Measures include strength assessments, muscle size, and performance of functional tasks.

Official TitleAuto-regulated Resistance-training for Improving Strength in Older Adults
Principal SponsorUniversity of Saskatchewan
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

36 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

AtrophyMuscular AtrophyNervous System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsPathological Conditions, AnatomicalNeuromuscular ManifestationsSarcopenia

Criteria

1 inclusion criteria required to participate
Males and females 50 years of age or greater

1 exclusion criteria prevent from participating
Inability to safely perform squat and bench press exercises as determined by the Get Active Questionnaire

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

3 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Participants complete their resistance-training sets to termination based on reaching a critical slow velocity

Group II

Experimental
Participants complete their resistance-training sets to termination based on rating of perceived exertion

Group III

Active Comparator
Participants complete their resistance-training sets by lifting a prescribed percentage of their estimated one-repetition maximum (as determined from baseline four-repetition maximum strength testing)

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

University of Saskatchewan

Saskatoon, CanadaOpen University of Saskatchewan in Google Maps
CompletedOne Study Center