Completed

TFP Block vs ESPB for Inguinal Hernia Repair Post-operative Analgesia

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Study Aim

This study aims to compare the effectiveness of TFP Block and ESPB for reducing post-operative pain intensity in individuals undergoing inguinal hernia repair, measured on a scale from 0 to 10.

What is being tested

Transversalis fascia plane (TFP) block

+ Erector Spinae Plane (ESP) Block

Procedure
Who is being recruted

Neurologic Manifestations+4

+ Pain

+ Pain, Postoperative

From 20 to 65 Years
+9 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Placebo-Controlled
Interventional
Study Start: December 2022
See protocol details

Summary

Principal SponsorAssiut University
Last updated: March 18, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: December 1, 2022

Actual date on which the first participant was enrolled.

This study focuses on improving pain management after inguinal hernia repair surgery, a common procedure worldwide. The goal is to find better ways to control post-operative pain, as unmanaged pain can lead to complications. The study compares two types of regional blocks, which are methods of pain control that target specific areas of the body. These are the Ultrasound-guided Transversalis Fascia Plane Block and the Erector Spinae Plane Block. Both methods involve injecting a local anesthetic into specific areas to block pain signals. The study aims to reduce reliance on opioid painkillers, which can cause side effects like itching, nausea, and breathing problems. During the study, participants receive one of the two types of blocks before their surgery. The Ultrasound-guided Transversalis Fascia Plane Block involves injecting the anesthetic between the transversus abdominis muscle and its deep investing fascia. The Erector Spinae Plane Block involves injecting the anesthetic between the erector spinae muscle and thoracic transverse process. The study measures the intensity of post-operative pain using a verbal scale from 0 to 10, with 0 representing no pain and 10 representing the worst possible pain.

Official TitleUltrasound-guided Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Post-operative Analgesia in Inguinal Hernia Repair Under General Anesthesia: a Randomized Controlled Study
NCT05565365
Principal SponsorAssiut University
Last updated: March 18, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

43 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Male

Biological sex of participants that are eligible to enroll.

From 20 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Neurologic ManifestationsPainPain, PostoperativePathologic ProcessesPostoperative ComplicationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Criteria

1 inclusion criteria required to participate
Male patients undergoing elective open unilateral inguinal hernia repair under general anesthesia, ASA status I-II, aged from 20 to 65 years old

8 exclusion criteria prevent from participating
Contraindications to regional block (coagulopathy, infection at the needle insertion site, or diaphragmatic paralysis)

Altered cognitive function

Body mass index (BMI > 35 kg/m2)

Patients who have difficulty understanding the study protocol

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Placebo
Patients will receive unilateral US-TFP block with bupivacaine 15 minutes before skin incision

Group II

Active Comparator
Patients will receive unilateral US-ESP block with bupivacaine 15 minutes before skin incision

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Assiut University

Asyut, EgyptOpen Assiut University in Google Maps
CompletedOne Study Center