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Brain Stimulation Effects on Cognitive Task Performance

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What is being tested

Transcranial Magnetic Stimulation

Device
Who is being recruted

From 18 to 65 Years
+24 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Other Study

Placebo-Controlled
Interventional
Study Start: April 2023
See protocol details

Summary

Principal SponsorColorado State University
Study ContactMichael Thomas, PhD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: April 20, 2023

Actual date on which the first participant was enrolled.

Transcranial magnetic stimulation (TMS) is a non-invasive form of brain stimulation that relies on rapidly changing magnetic fields to influence neuronal firing rates. TMS can be used to temporarily inhibit or enhance the firing of populations of neurons located in the cerebral cortex. TMS-induced cortical inhibition versus enhancement is increasingly being used as a tool for exploring brain-behavior relationships and for improving cognitive functioning in people experiencing cognitive deficits due to neuropsychiatric illness (e.g., dementia and schizophrenia). However, important and unresolved methodological issues in this field concern the optimal design of cognitive tasks for TMS stimulation protocols. The purpose of this study is to determine optimal design protocols for online TMS studies of cognitive processes involved in attention, learning, and memory. Research participants will complete cognitive tasks while active versus sham (i.e., non-stimulating) TMS is applied to the brain. A factorial design will be used to determine the combination of task and TMS parameters (i.e., device settings) that produce the most robust and reliable behavioral effects.

Official TitleBrain Stimulation Effects on Cognitive Task Performance
Principal SponsorColorado State University
Study ContactMichael Thomas, PhD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

100 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Other Study

Some studies explore topics that don't fall into a specific category. These might include innovative research, new technologies, or emerging healthcare areas.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 65 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

2 inclusion criteria required to participate
Right-handed

Fluent in English

22 exclusion criteria prevent from participating
History of seizures or epilepsy

Family history of epilepsy

Significant medical or neurological diagnoses

History of common headache or migraine

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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
Repetitive TMS for the brain

Group II

Placebo
Scalp stimulation that does not affect the brain.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Colorado State University Department of Psychology

Fort Collins, United StatesOpen Colorado State University Department of Psychology in Google Maps
Recruiting
One Study Center