Completed

The Effect of Hydrogen-rich Water Consumption on Premenstrual Symptoms and Quality of Life in Students With Premenstrual Syndrome: A Randomized Controlled Study

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What is being tested

Hydrogenated water consumption

+ Drinking water consumption

Other
Who is being recruted

Menstruation Disturbances+1

+ Pathologic Processes

+ Premenstrual Syndrome

Over 18 Years
See all eligibility criteria
How is the trial designed

Supportive Care Study

Placebo-Controlled
Interventional
Study Start: October 2022
See protocol details

Summary

Principal SponsorMenekşe Nazlı AKER
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 1, 2022

Actual date on which the first participant was enrolled.

The aim of this study is to determine the effect of hydrogenated water on premenstrual symptoms and quality of life in students with premenstrual syndrome. Research Hypotheses H1 1 Hydrogenated water consumption reduces premenstrual symptoms in students with premenstrual syndrome. H1 2 Hydrogenated water consumption increases the quality of life in students with premenstrual syndrome. The research will consist of intervention and control groups. Individuals consuming hydrogen-rich water will be included in the intervention group, whereas individuals consuming normal water will be in the control group. The block randomization method will be used to randomly assign participants who meet the research criteria to the groups. Participants will be provided with hydrogenated water for three cycles.

Official TitleThe Effect of Hydrogen-rich Water Consumption on Premenstrual Symptoms and Quality of Life in Students With Premenstrual Syndrome: A Randomized Controlled Study
Principal SponsorMenekşe Nazlı AKER
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

72 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Supportive Care Study

These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Female

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Menstruation DisturbancesPathologic ProcessesPremenstrual SyndromePathological Conditions, Signs and Symptoms

Criteria

Inclusion Criteria: * The length of the menstrual cycle is within normal limits (21-35), * Getting a score of 132 or more from the Premenstrual Syndrome Scale, * Not receiving medical treatment for PMS, * Not having any psychiatric diagnosis. Exclusion Criteria: * • Irregular menstruation in the last three cycles * Having received a psychiatric diagnosis, * Having any gynecological disease (abnormal uterine bleeding, myoma, ovarian cyst, etc.) * Using contraceptive medication. * Individuals' refusal to participate in the study, * Participants' non-compliance with the research plan, * Participants start receiving PMS treatment during the study period.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental

Group II

Placebo

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Ankara University Faculty of Nursing

Altindağ, Turkey (Türkiye)Open Ankara University Faculty of Nursing in Google Maps
CompletedOne Study Center