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PHFMIMethods for Predicting Heart Failure Development After Myocardial Infarction

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Study Aim

This observational study aims to predict the development of heart failure after a myocardial infarction (heart attack) by analyzing events such as cardiovascular death, nonfatal heart attacks, any type of stroke, and hospitalization due to chronic heart failure decompensation.

What is being collected

Data Collection

Collected from today forward - Prospective
DNA Samples
Who is being recruted

Cardiovascular Diseases+8

+ Heart Diseases

+ Heart Failure

From 18 to 70 Years
+13 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: January 2019
See protocol details

Summary

Principal SponsorNovosibirsk State Medical University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2019

Actual date on which the first participant was enrolled.

This study is about finding ways to predict the development of heart failure after a person has had a heart attack, also known as myocardial infarction. The study is focused on patients who have been admitted to a specific hospital in Novosibirsk, Russia. The goal is to understand how heart failure develops after a heart attack, which could help doctors improve care and treatment for these patients. This research is important because heart failure is a common and serious complication after a heart attack, and being able to predict who is at risk could lead to better prevention and management strategies. During the study, patients will undergo various examinations at different points in time: on the first day of hospitalization, 30 days after the heart attack, and 12 months later. These examinations include clinical assessments, lab tests, and imaging studies like ECG and chest X-rays. Some patients may also have procedures like coronary angiography and percutaneous coronary intervention. The study will look at the results of these examinations to see if they can help predict who will develop heart failure. The primary outcome being measured is a combination of cardiovascular death, nonfatal myocardial infarction, stroke of any type, and hospitalization due to decompensation of chronic heart failure.

Official TitleSearch for Methods to Predict the Development of Heart Failure After Myocardial Infarction
Principal SponsorNovosibirsk State Medical University
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

186 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 70 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Cardiovascular DiseasesHeart DiseasesHeart FailureInfarctionIschemiaMyocardial InfarctionNecrosisPathologic ProcessesPathological Conditions, Signs and SymptomsVascular DiseasesMyocardial Ischemia

Criteria

3 inclusion criteria required to participate
women and men aged 18-75 years;

hospitalization in the cardiology department for treatment of patients with myocardial infarction at City Clinical Hospital No. 1 with confirmed acute myocardial infarction, typical clinical picture, electrocardiography data, results of cardiospecific enzymes (troponin I, MB fraction of creatine phosphokinase (MB-CPK));

signing of voluntary informed consent to participate in the research work

10 exclusion criteria prevent from participating
acute inflammatory diseases;

chronic diseases in the phase of exacerbation and/or incomplete remission;

diabetes mellitus type 1;

severe hepatic and renal insufficiency (glomerular filtration rate according to CKD-EPI formula <15 ml/min/1.73m2);

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Novosibirsk State Medical University

Novosibirsk, RussiaOpen Novosibirsk State Medical University in Google Maps
SuspendedOne Study Center