Suspended

EASY-CAREEASY CARE Early Neurological Assessment With Pupillometry in Cardiac Arrest During Resuscitation

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Cardiovascular Diseases+1

+ Heart Arrest

+ Heart Diseases

Over 18 Years
+9 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: December 2022
See protocol details

Summary

Principal SponsorSocieta Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Study ContactSimone M Zerbi, MDMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: December 1, 2022

Actual date on which the first participant was enrolled.

At the arrival of medicalised rescue team on the emergency scene, patient will be screened for including criteria. In case of eligibility pupillometry will be collected each eye in the following frame time: * T 0: time of enrolling * T 1: after first cycle of resuscitation (approximatively 2 minutes following guidelines) * T 2 … Tn: every cycle of CPR (or every 2 minutes if intubated patient) bilateral pupillometry will be collected * T end: the last pupillometry at ROSC time or death. All pupillometry mesures will be obtained from a technician not trained to interpret NPi index. This to maintain blindness during resuscitation efforts. Data will be collected in anonymous web-based database passwords protected. For the survivors patients enrolled, data collecting continue in Intensive Care Unit (ICU) as neuroprognostication exams (biomarkers, imaging, neurophysiology). Blind follow up will be obtained from ICU as described in secondary outcome section

Official TitleEASY CARE Early Neurological Assessment With Pupillometry in Cardiac Arrest During Resuscitation
Principal SponsorSocieta Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva
Study ContactSimone M Zerbi, MDMore contacts
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

214 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Cardiovascular DiseasesHeart ArrestHeart DiseasesOut-of-Hospital Cardiac Arrest

Criteria

3 inclusion criteria required to participate
Not traumatic cardiac arrest in pre-hospital setting (OHCA)

unexpected OHCA

Lombardy region territory

6 exclusion criteria prevent from participating
Traumatic Brain injury

Cerebrovascular emergecies at computer tomography (CT) scan after hospital admission

Peripheral or cortical blindness

One or both eyes loss

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Agenzia Regionale Emergenza Urgenza - AREU

Milan, ItalyOpen Agenzia Regionale Emergenza Urgenza - AREU in Google Maps
SuspendedOne Study Center