Completed

The Effect of Menstrual Cycle Phase and Protein Dose on Muscle Protein Synthesis in Response to Exercise in Young Females

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What is being tested

Dose of protein

+ Menstrual cycle phase

Dietary SupplementOther
Who is being recruted

From 18 to 40 Years
+12 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Basic Science Study

Interventional
Study Start: January 2022
See protocol details

Summary

Principal SponsorUniversity of Exeter
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 16, 2022

Actual date on which the first participant was enrolled.

Adaptation to resistance exercise requires maximal rates of muscle protein synthesis, which can be achieved with post-exercise ingestion of \~20g of protein. These recommendations are based on studies in males and responses in females may vary. Muscle recovery is related to the ability to build new muscle protein from amino acids (muscle protein synthesis). This response is thought to be impacted in females by hormones that fluctuate across different phases of the menstrual cycle. However, the effect of menstrual cycle phase on muscle protein synthesis is not known.

Official TitleThe Effect of Menstrual Cycle Phase and Protein Dose on Muscle Protein Synthesis in Response to Exercise in Young Females
NCT05178732
Principal SponsorUniversity of Exeter
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

28 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Female

Biological sex of participants that are eligible to enroll.

From 18 to 40 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

3 inclusion criteria required to participate
BMI between 18 and 30
Recreationally active
Regular menstrual cycle
9 exclusion criteria prevent from participating
Smoking
Metabolic disease
Any motor disorder
Use of over-the-counter pharmaceuticals, during the study.
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

6 intervention groups are designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental

Group II

Experimental

Group III

Experimental

Group IV

Experimental

Group 5

Experimental

Group 6

Experimental

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

University of Exeter

Exeter, United KingdomOpen University of Exeter in Google Maps
CompletedOne Study Center