Intravenous Lidocaine and Alfentanil for Cough Prevention in Bronchoscopic Procedures

The study investigates the effects of adding two drugs, lidocaine and alfentanil, given intravenously before a bronchoscopy procedure. This procedure often causes patients to cough, which can lead to complications like airway spasms or interruptions during the procedure. The research focuses on people undergoing bronchoscopic interventions without endotracheal tubes, where steady airways are crucial. The goal is to see if these medications can effectively reduce cough and improve the procedure's success, addressing a common problem faced during bronchoscopic procedures. Participants in the study receive either lidocaine, alfentanil, or a saline solution injected into their veins one minute before the bronchoscope is inserted. Researchers then record various responses including the severity of cough, visibility during the procedure, and reactions of the vocal cords. They also measure levels of anesthesia, pain response, blood pressure, heart rate, and oxygen levels in the blood. By evaluating these factors, the study aims to determine if these drugs can reduce cough intensity and improve patient stability during the procedure.