Completed

Role of Oral Steroids in Reducing Recurrence of Urethral Stricture After Direct Vision Internal Urethrotomy

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What is being tested

Steroid Drug

+ No steroid

Drug
Who is being recruted

Pathologic Processes+1

+ Recurrence

+ Pathological Conditions, Signs and Symptoms

From 20 to 60 Years
+6 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Placebo-Controlled
Interventional
Study Start: January 2018
See protocol details

Summary

Principal SponsorServices Hospital, Lahore
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 1, 2018

Actual date on which the first participant was enrolled.

It was a randomized controlled trial conducted at department of Urology, Armed Forces Institute of Urology, Rawalpindi from 1st January, 2018 July 2019 to 31st March 2021 to determine the role of oral steroids after Direct Vision Internal Urethrotomy to reduce the recurrence rate of urethral strictures.

Official TitleRole of Oral Steroids in Reducing Recurrence of Urethral Stricture After Direct Vision Internal Urethrotomy
NCT05069883
Principal SponsorServices Hospital, Lahore
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

180 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Male

Biological sex of participants that are eligible to enroll.

From 20 to 60 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Pathologic ProcessesRecurrencePathological Conditions, Signs and SymptomsDisease Attributes

Criteria

1 inclusion criteria required to participate
Patients with urethral stricture with restricted urine flow of < 15 ml/min on uroflowmetry
5 exclusion criteria prevent from participating
Patients presenting with post-anastomotic urethroplasty strictures (assessed on history and medical record),
Patients with post-TURP strictures
Patients with neurogenic bladder
Patients with prior history of steroid use
Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental
In this group oral steroids were given after Direct vision internal urethrotomy

Group II

Placebo
In this group no oral steroids were given after Direct vision internal urethrotomy

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Armed Force Institute of Urology

Rawalpindi, PakistanOpen Armed Force Institute of Urology in Google Maps
CompletedOne Study Center