Completed

Treatment of Ruptured and Unruptured Wide-Neck Aneurysms With Nautilus™ Device Assisted Occlusion (TORNADO)

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Nautilus endovascular device

Device
Who is being recruted

Aneurysm+6

+ Brain Diseases

+ Cardiovascular Diseases

Over 18 Years
See all eligibility criteria
How is the trial designed

Treatment Study

Interventional
Study Start: March 2021
See protocol details

Summary

Principal SponsorEndoStream Medical
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: March 17, 2021

Actual date on which the first participant was enrolled.

Patients will be treated with the Nautilus, then will be followed up for up to 6 months.

Official TitleTreatment of Ruptured and Unruptured Wide-Neck Aneurysms With Nautilus™ Device Assisted Occlusion (TORNADO)
NCT04963933
Principal SponsorEndoStream Medical
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

30 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

AneurysmBrain DiseasesCardiovascular DiseasesCentral Nervous System DiseasesIntracranial AneurysmCerebrovascular DisordersNervous System DiseasesVascular DiseasesIntracranial Arterial Diseases

Criteria

Inclusion Criteria: \* Patients who present with intracranial aneurysm Exclusion Criteria: \* Unstable neurological deficit

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Patients treated with the Nautilus will be followed up

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 2 locations

Suspended

St. Ivan Rilski University hospital

Sofia, BulgariaOpen St. Ivan Rilski University hospital in Google Maps
Suspended

Paula Stradina university hospital

Riga, Latvia
Completed2 Study Centers