Completed

ABDO-VMUltrasound Evaluation of Abdominal Muscle Thickness During Mechanical Ventilation

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What is being tested

Ultrasound

Device
Who is being recruted

Over 18 Years
+7 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Diagnostic Study

Interventional
Study Start: July 2021
See protocol details

Summary

Principal SponsorCentre Hospitalier de Roanne
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: July 15, 2021

Actual date on which the first participant was enrolled.

Weakness of respiratory muscles is frequent after several days of mechanical ventilation. Thereby an acquired diaphragm weakness has been demonstrated, linked to an atrophy which may be identified by a decrease of muscle thickness in echography. Weakness of expiratory muscles is also frequent after 7 days of mechanical ventilation, however his cause is not clear: is it present at admission notably in elderly patients, or acquired on mechanical ventilation ? Ultrasound allows to measure the thickness of abdominal muscles which correlates with their strength. This study aims to evaluate with ultrasound the variation of thickness of abdominal muscles after 7 days of mechanical ventilation.

Official TitleUltrasound Evaluation of Abdominal Muscle Thickness During Mechanical Ventilation
NCT04939298
Principal SponsorCentre Hospitalier de Roanne
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

40 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Diagnostic Study

Diagnostic studies focus on improving how we detect or confirm a disease. They test new tools or techniques that could provide faster or more accurate diagnoses.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

3 inclusion criteria required to participate
Patient affiliated or entitled to a social security plan
Expected duration of mechanical ventilation > 7 days
Trusted person/relative who has signed a consent to participate in the study
4 exclusion criteria prevent from participating
Patient with a pre-existing neuromuscular pathology
No access to ultrasound Windows (dressing, drainages...)
Patient transferred from another intensive care unit
Patient Under guardianship or curators

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Ultrasound evaluation of the variation of thickness of abdominal muscles after 7 days of mechanical ventilation

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Centre Hospitalier de Roanne

Roanne, FranceOpen Centre Hospitalier de Roanne in Google Maps
CompletedOne Study Center