Impact of Exercise Training on Vascular Dysfunction in Individuals with Mental Health Disorders
This study aims to investigate how exercise training affects vascular function in individuals with mental health disorders, focusing on changes in arm and leg blood flow at rest and in response to exercise.
Antioxidant
+ Placebo
Trauma and Stressor Related Disorders+4
+ Mental Disorders
+ Cardiovascular Diseases
Basic Science Study
Summary
Study start date: August 23, 2021
Actual date on which the first participant was enrolled.This study focuses on understanding how exercise training impacts vascular dysfunction in individuals with mental health disorders. It's a basic science study, which means it's designed to explore how certain things work in the body. The study is specifically interested in people with mental health disorders, as they may have unique vascular responses. The goal is to learn more about blood vessel health in this group, which could potentially improve care and treatment options. The study consists of three sessions, each held on a separate day, and can be completed in as little as two weeks. The first session is an introduction to the study equipment and procedures, and involves measuring body metrics like height, weight, and body fat, as well as determining forearm and calf strength. The next two sessions involve multiple tests to evaluate blood vessel health. In one session, participants will receive antioxidant pills, and in the other, they will receive placebo pills. This is to understand the role of oxidants in blood vessel health. The study measures changes in blood flow and artery dilation in response to rest and exercise, as well as during a passive leg movement test.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.720 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Basic Science Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.From 18 to 35 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.2 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
ExperimentalGroup II
ExperimentalStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Virginia Commonwealth University
Richmond, United StatesOpen Virginia Commonwealth University in Google Maps