Completed

T-RexNon-interventional, Multicenter Retrospective Study of the Effectiveness and Safety of Teduglutide (Revestive®) in Short Bowel Syndrome Adult Patients in Spain (T-Rex Study)

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What is being collected

Data Collection

Collected from past medical records and data - Retrospective
Who is being recruted

Digestive System Diseases+5

+ Gastrointestinal Diseases

+ Intestinal Diseases

Over 18 Years
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: January 2022
See protocol details

Summary

Principal SponsorTakeda
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: January 26, 2022

Actual date on which the first participant was enrolled.

The main aims of the study are to assess the safety profile of teduglutide (Revestive®) as well as how many people with Short Bowl Syndrome experience a reduction of parenteral support when treated with teduglutide (Revestive®). This study is about collecting existing data only; participants will not receive teduglutide (Revestive®) as part of this study. No new information will be collected during this study. Only data already available in the hospital records will be reviewed and collected for this study. Participants do not need to visit their doctor in addition to their normal visits.

Official TitleNon-interventional, Multicenter Retrospective Study of the Effectiveness and Safety of Teduglutide (Revestive®) in Short Bowel Syndrome Adult Patients in Spain (T-Rex Study)
NCT04883606
Principal SponsorTakeda
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

65 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Digestive System DiseasesGastrointestinal DiseasesIntestinal DiseasesMalabsorption SyndromesPathologic ProcessesPostoperative ComplicationsShort Bowel SyndromePathological Conditions, Signs and Symptoms

Criteria

Inclusion Criteria: * Participants \>= 18 years of age diagnosed with intestinal failure due to SBS as a result of intestinal resection. * SBS-IF participants treated with teduglutide according to Summary of Product Characteristics (SmPC). * Patients who receive or have received teduglutide for at least six months at the date of inclusion (from treatment initiation to inclusion date, date of discontinuation, death for any cause or loss of follow-up). * When required by the ethics committee of the center: participants who have signed the informed consent form (ICF) to participate in the study. Exclusion Criteria: \- Participants who do not meet the inclusion criteria.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Hospital Universitari de Bellvitge

L'Hospitalet de Llobregat, SpainOpen Hospital Universitari de Bellvitge in Google Maps
CompletedOne Study Center