DESSRTDose-Escalated Spine SbRT for Localized Spinal Metastasis
This study aims to evaluate how dose-escalated spine Stereotactic Body Radiotherapy affects pain, quality of life, and well-being in patients with localized spinal metastasis.
Spine stereotactic body radiotherapy
Treatment Study
Summary
Study start date: March 14, 2021
Actual date on which the first participant was enrolled.This study is exploring a new treatment method for people with cancer that has spread to their spine, known as localized spine metastasis. Traditional methods, like external-beam radiotherapy, have limitations, so researchers are using a technique called spine stereotactic radiosurgery as an alternative. This method has shown promise over the past decade in controlling pain and improving nerve function in patients who have compression of the spine. The study is important because it could offer better pain management and improve quality of life for those dealing with this challenging condition. Participants in this study undergo a specialized form of radiation therapy, called Stereotactic Body Radiotherapy (SBRT), which is directed precisely at the spine. The treatment aims to see how well it controls pain and other symptoms. Researchers use several tools to measure the outcomes: the Brief Pain Inventory assesses pain levels, the EQ-5D-5L evaluates overall health dimensions like mobility and anxiety, and the FACT-G measures well-being in physical, social, emotional, and functional areas. By collecting this data, the study evaluates the effectiveness and tolerability of this escalated dose treatment, which could lead to better care practices for patients with spine metastases.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.60 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.One single intervention group is designated in this study
This study does not include a placebo group
Treatment Groups
Group I
Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Miami Cancer Institute at Baptist Health, Inc
Miami, United StatesOpen Miami Cancer Institute at Baptist Health, Inc in Google Maps