Completed

1L- vs. 4L-Polyethylene Glycol for Bowel Preparation Before Colonoscopy Among Inpatients: a Propensity Score-matching Analysis.

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Over 18 Years
+3 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Case-Control

Comparing exposures between individuals with and without disease in order to identify potential risk factors.
Observational
Study Start: February 2019
See protocol details

Summary

Principal SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: February 1, 2019

Actual date on which the first participant was enrolled.

Background and aims: Inpatients are at high risk for inadequate colon cleansing. Experts recommend 4L-polyethylene-glycol (PEG) solution because of its effectiveness and safety profile. A higher colon cleansing adequacy rate for a hyperosmolar 1L-PEG plus ascorbate prep has been recently reported in an observational study among more than 1,000 inpatients. Thus, the present study is aimed at determining whether 1L-PEG outperforms 4L-PEG among inpatients, through a propensity score-matching between the two groups in order to correct for confounders.

Official Title1L- vs. 4L-Polyethylene Glycol for Bowel Preparation Before Colonoscopy Among Inpatients: a Propensity Score-matching Analysis.
NCT04310332
Principal SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

1004 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-Control

These studies compare people who have a disease (cases) with those who don't (controls). The goal is to look back at previous exposures or risk factors to identify what might have contributed to the disease.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

1 inclusion criteria required to participate
Adult inpatients scheduled for colonoscopy for any indication within the normal process of care.
2 exclusion criteria prevent from participating
patients who underwent emergency or elective therapeutic colonoscopies (e.g. polypectomy, endoscopic mucosal resection, endoscopic submucosal dissection)
patients who underwent bowel preparation outside the hospital

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 10 locations

Suspended

Policlinico Sant'Orsola-Malpighi

Bologna, ItalyOpen Policlinico Sant'Orsola-Malpighi in Google Maps
Suspended

Digestive Endoscopy Unit, Fondazione Poliambulanza

Brescia, Italy
Suspended

UOSD Gastroenterologia ed Endoscopia Digestiva, Azienda USL di Modena

Carpi, Italy
Suspended

Gastroenterology Unit, Valduce Hospital

Como, Italy
Completed10 Study Centers