Suspended
The Hypoglycemic Effect of Cyclocarya Paliurus Extract on Hyperglycemic Populations
What is being tested
Cyclocarya paliurus extract
+ Cyclocarya paliurus compounds
+ placebo
Dietary Supplement
Who is being recruted
Diabetes Mellitus+4
+ Endocrine System Diseases
+ Hyperglycemia
From 20 to 65 Years
+10 Eligibility Criteria
How is the trial designed
Prevention Study
Placebo-Controlled
Interventional
Study Start: March 2020
Summary
Principal SponsorHuazhong University of Science and Technology
Study ContactLiegang Liu, PhDMore contacts
Last updated: January 28, 2026Sourced from a government-validated database.Claim as a partner
Study start date: March 1, 2020
Actual date on which the first participant was enrolled.This is a randomized double-blind controlled trial，aiming to investigate the hypoglycemic effect of Cyclocarya paliurus extract and Cyclocarya paliurus compounds on hyperglycemic populations without modifying their original treatment plans.
Official TitleThe Hypoglycemic Effect of Cyclocarya Paliurus Extract on Hyperglycemic Populations
Principal SponsorHuazhong University of Science and Technology
Study ContactLiegang Liu, PhDMore contacts
Last updated: January 28, 2026Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
150 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Prevention Study
Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.From 20 to 65 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Diabetes MellitusEndocrine System DiseasesHyperglycemiaMetabolic DiseasesNutritional and Metabolic DiseasesGlucose IntoleranceGlucose Metabolism Disorders
Criteria
3 inclusion criteria required to participate
pre-diabetic or type 2 diabetic patients who are treated with only one oral antidiabetic agent and whose fasting plasma glucose is lower than 8.4 mmol;
age:20-65 years;
BMI :20-35kg/m2.
7 exclusion criteria prevent from participating
type 1 diabetic patients;
type 2 diabetic patients with insulin treatment；
pregnant or lactating women；
adverse effect on intervention；
Show More Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Treatment Groups
Study Objectives
3 intervention groups are designated in this study
33.333% chance of being blinded to the placebo group
Treatment Groups
Group I
Experimentalaqueous extract of Cyclocarya paliurus；capsule，2 g/day，2 times/day；3 months
Group II
Experimentalmixed aqueous extract of Cyclocarya paliurus and other traditional Chinese herbal medicines including Astragalus propinquus Schischkin，Dioscorea oppositifolia L.，Dendrobium nobile Lindl.，Salvia miltiorrhiza Bge. and Inulin；capsule，2 g/day，2 times/day；3 months
Group III
Placebocorn starch；capsule，2 g/day，2 times/day；3 months
Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
SuspendedOne Study Center