Completed

Low GI Diet Impact on Cardiometabolic Risk Factors in Obese Chinese Adults

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Study Aim

This study aims to evaluate the impact of a low glycemic index (GI) diet on body mass index (BMI) in obese Chinese adults, by comparing changes in BMI within and between participants.

What is being tested

Low GI diet

Behavioral
Who is being recruted

Body Weight+6

+ Nutrition Disorders

+ Nutritional and Metabolic Diseases

Over 18 Years
+12 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Treatment Study

Placebo-Controlled
Interventional
Study Start: March 2021
See protocol details

Summary

Principal SponsorChinese University of Hong Kong
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: March 1, 2021

Actual date on which the first participant was enrolled.

Obesity affects nearly 30% of adults in Hong Kong, leading to serious health issues like high blood pressure, heart disease, and type 2 diabetes. One dietary approach that has shown promise in managing weight is the low Glycemic Index (GI) diet. However, most studies on low GI diets have been conducted in Western populations, leaving a gap in understanding its effects on Chinese adults. This study aims to explore the impact and acceptability of a low GI diet compared to a conventional healthy diet on the Body Mass Index (BMI) and other heart-related risk factors in obese Chinese adults living in Hong Kong. The study is designed as a two-arm randomized controlled trial. Participants in the intervention group will receive education on a low GI diet, including a 60-minute face-to-face session with a research nurse and an informational booklet. This will be followed by three 15-minute phone calls at the 2nd, 5th, and 8th weeks. The control group will receive educational pamphlets on obesity and balanced diets, also followed by three 15-minute phone calls at the same intervals. At the start and end of the 12-week period, data on BMI, waist circumference, body fat, blood pressure, blood sugar levels, and other related factors will be collected to measure the effects of the diet.

Official TitleThe Effects of Low Glycemic Index (GI) Diet on Cardiometabolic Outcomes Among Obese Chinese Adults: A Randomized Controlled Trial
NCT04152213
Principal SponsorChinese University of Hong Kong
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

166 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Body WeightNutrition DisordersNutritional and Metabolic DiseasesObesitySigns and SymptomsPathological Conditions, Signs and SymptomsOvernutritionOverweightObesity, Abdominal

Criteria

7 inclusion criteria required to participate
BMI >25.0 kg/m2;

Waist circumference > 90 cm for men and > 80 cm for women;

Aged eighteen years or older;

Chinese ethnicity;

Show More Criteria

5 exclusion criteria prevent from participating
Concurrently participating in any other clinical trials;

Concurrently participating in weight control programs;

Concomitant intake of weight reduction drugs;

Use of calorie restricted diet or specialized diets which contraindicated with low GI diet;

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Placebo
The components of the control group include: (1) Pamphlets from the Department of Health about obesity and a balanced diet based on the food pyramid will be distributed. (2)Three follow-up telephone calls of fifteen minutes will be conducted by the research nurse at the 2nd, 5th , and 8th weeks after receiving the pamphlets.

Group II

Experimental
The components of the Low GI diet group include: (1) A one-off, 60-minute, face-to-face, educational session conducted by the research nurse for GI knowledge input. (2) An informational booklet will be given out during the education session. (3) Three follow-up telephone calls of fifteen minutes will be conducted by the research nurse at the 2nd, 5th , and 8th weeks after completing the face-to-face education session.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

District Councilor Office

Hong Kong, Hong KongOpen District Councilor Office in Google Maps
CompletedOne Study Center