Suspended

UWFA-RVO-MEUltra-wide-field Fluorescein Angiography in Patients With Macular Edema Secondary to Retinal Vein Occlusion

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What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Cardiovascular Diseases+8

+ Eye Diseases

+ Macular Degeneration

Over 18 Years
+14 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: October 2023
See protocol details

Summary

Principal SponsorRenmin Hospital of Wuhan University
Study ContactCZ Chen, PHD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: October 9, 2023

Actual date on which the first participant was enrolled.

Ultra-wide field fluorescence angiography can clearly observe the peripheral retina. This study mainly observes the ischemic index and vascular leakage index changes on UWFA after anti-VEGF treatment and evaluates these changes associated with treatment efficacy in patients with macular edema secondary to retinal vein occlusion.

Official TitleUltra-wide-field Fluorescein Angiography in Patients With Macular Edema Secondary to Retinal Vein Occlusion
NCT04140448
Principal SponsorRenmin Hospital of Wuhan University
Study ContactCZ Chen, PHD
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

60 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Cardiovascular DiseasesEye DiseasesMacular DegenerationMacular EdemaRetinal DegenerationRetinal DiseasesRetinal Vein OcclusionThrombosisVascular DiseasesEmbolism and ThrombosisVenous Thrombosis

Criteria

5 inclusion criteria required to participate
Male or female aged 18 years or older

Macular edema secondary to CRVO,BRVO or HRVO

Duration of RVO not more than 4 months

Naïve patients. Patient with previous RVO (more than 12 months before the inclusion date) completely resolved (normalization of visual acuity and fundus examination) and who have experienced a recurrence of RVO are also considered naive

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9 exclusion criteria prevent from participating
Patient with another retinal disease in the study eye: diabetic retinopathy, maculopathy of any cause (age-related macular degeneration, epimacular membrane, myopia, etc) responsible for decreased vision, advanced glaucoma, cataract severely affecting vision and/or requiring surgical treatment during the 24 months study period

Active or suspected ocular or periocular infection

Active severe intraocular inflammation

RVO complicated with neovascularization

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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Renmin Hospital of Wuhan University

Wuhan, ChinaOpen Renmin Hospital of Wuhan University in Google Maps
SuspendedOne Study Center