Completed
ENDOMOHEndocrinological Profile in Patients With Medication-overuse Headache Before
What is being collected
Data Collection
Collected from today forward - ProspectiveNo DNA Sample
Who is being recruted
Brain Diseases+5
+ Central Nervous System Diseases
+ Endocrine System Diseases
From 18 to 60 Years
+11 Eligibility Criteria
How is the trial designed
Cohort
Tracking disease incidence in order to identify risk factors and understand disease progression over time.Observational
Study Start: August 2019
Summary
Principal SponsorDanish Headache Center
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner
Study start date: August 1, 2019
Actual date on which the first participant was enrolled.The project will be conducted to investigate the hormonal homeostasis in men and women, with a special emphasis on sex hormones in men and AMH level in women, before and after withdrawal of the overused analgesics among MOH patients. Additionally, a more broad endocrine profile will be explored before and after withdrawal. It is hypothesized that patients with MOH have disturbed hormone levels, which is normalized after withdrawal of the medication-overuse.
Official TitleEndocrinological Profile in Patients With Medication-overuse Headache Before
Principal SponsorDanish Headache Center
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
50 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Cohort
These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.From 18 to 60 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Brain DiseasesCentral Nervous System DiseasesEndocrine System DiseasesMigraine DisordersNervous System DiseasesHeadache DisordersHeadache Disorders, PrimaryHeadache Disorders, Secondary
Criteria
5 inclusion criteria required to participate
Confirmed MOH diagnosis according to the ICHD-III (1).
Capable of completing headache diary and headache calendar
Age 18-60 years old for men and 18-50 years old for women
Signed informed consent
Show More Criteria
6 exclusion criteria prevent from participating
Severe physical illness
Severe psychiatric disorders requiring pharmacological treatment
Addiction to alcohol or other drugs
Pregnancy or breastfeeding
Show More Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Study Objectives
Primary Objectives
Secondary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Suspended
CompletedOne Study Center