Polymorphisms in the Kisspeptin/GPR54 Pathway Genes and the Risk of Early Puberty
Data Collection
Collected from past medical records and data - RetrospectiveEndocrine System Diseases
+ Gonadal Disorders
+ Puberty, Precocious
Case-Control
Comparing exposures between individuals with and without disease in order to identify potential risk factors.Summary
Study start date: September 1, 2016
Actual date on which the first participant was enrolled.There was a worldwide early trend in girls'age for puberty onset. The timing of puberty onset varies greatly among individuals, and much of this variation is modulated by genetic factors. This study was designed to explored the association of polymorphisms in KISS1/GPR54 pathway genes and the risk of early puberty in Chinese Han girls.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.628 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Case-Control
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Female
Biological sex of participants that are eligible to enroll.From 7 to 10 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Inclusion Criteria: \- Clinical diagnosis of central precocious puberty or early and fast puberty. Exclusion Criteria: * The participants who were not the first visit to the hospital and had been treated before. * The participants who were with endocrine disorders.
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Primary Objectives