Completed

The Effectiveness of Virtual Reality Based Rehabilitation in Patients With Knee Osteoarthritis

What is being tested

Virtual Reality based Rehabilitation Program

Other

Who is being recruted

Kinesiophobia+7

+ Anxiety Disorders

+ Arthritis

From 40 to 75 Years

+10 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Treatment Study

Interventional

Study Start: April 2018

See protocol details

Summary

Principal SponsorIstanbul Medeniyet University

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: April 21, 2018

Actual date on which the first participant was enrolled.

Sixty volunteer participants with knee osteoarthritis aged 40 to 65 years who were at stage of 2-3 according to the Kellgren Lawrence radiological evaluation were included in the study. Participants were randomly divided into two groups as virtual and control group. While a conventional physiotherapy program consisting of electrotherapy and exercise program was applied to both groups 5 days a week for 6 weeks, a virtual reality program was added to the virtual group for 6 weeks, 5 days a week. At the beginning of the treatment and at the end of the sixth week, ROM, pain, kinesiophobia, proprioception, balance, muscle strength and functional status were evaluated between groups.

Official TitleThe Effectiveness of Virtual Reality Based Rehabilitation in Patients With Knee Osteoarthritis

NCT04011553

Principal SponsorIstanbul Medeniyet University

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

60 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Treatment Study

These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 40 to 75 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

KinesiophobiaAnxiety DisordersArthritisMental DisordersJoint DiseasesMusculoskeletal DiseasesOsteoarthritisPhobic DisordersRheumatic DiseasesOsteoarthritis, Knee

Criteria

1 inclusion criteria required to participate

knee osteoarhritis aged 40 to 75 years who were at stage of 2-3 according to the Kellegren Lawrence radiological evaluation were included in the study.

9 exclusion criteria prevent from participating

Those who have received physical therapy in the last 6 months

Having serious systemic and cardiovascular diseases that may prevent exercise

Neurological and orthopedic problems affecting gait

Those with sensory defects

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Treatment Groups

Study Objectives

2 intervention groups are designated in this study

This study does not include a placebo group

Treatment Groups

Group I

Active Comparator

Conventional physiotherapy consists of electrotherapy and exercise programs. Hotpack or coldpack, therapeutic ultrasound (US) and conventional TENS were applied as electrotherapy program.

Group II

Experimental

This virtual realtiy was implemented with MarVAJED® (Marmara Visual Auditory Joint Education Device) system which was developed by Marmara University, Department of Physiotherapy and Rehabilitation, Istanbul,Turkey. MarVAJED® is a system that evaulates the range of motion of the joints, analyzes the sensation of joint position, provides biofeedback support to increase joint control and the same time allows exercises to be controlled. This device analyzes the joint motion with the help of small sensors (Figure 2). The obtained data transfers to your mobile phone, to the tablet or to your personal computer. It stores the data by downloading it to the central server via internet for storage.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Istanbul Medeniyet University

Istanbul, Turkey (Türkiye)Open Istanbul Medeniyet University in Google Maps

CompletedOne Study Center