Evaluating the Ocular Function of Adults With Autism Spectrum Disorder: Interrelationship Between Blinking Reflex and Cornea Innervation.
Data Collection
Collected at a single point in time - Cross-sectionalAutism Spectrum Disorder+2
+ Autistic Disorder
+ Mental Disorders
Case-Control
Comparing exposures between individuals with and without disease in order to identify potential risk factors.Summary
Study start date: May 15, 2019
Actual date on which the first participant was enrolled.Anomalies in visual information processing can have a major effect on the life quality of individuals with autism spectrum disorders (ASD), including eye gaze abnormality, higher frequency of refractive errors (e.g., astigmatism, hypermetropia, and anisometropia), strabismus, abnormal blinking rate, disturbed eye movements that may be associated with or aggravated social communication deficits of ASD. However, little is known about the ocular surface conditions. This study will investigate the visual function in individuals with ASD, with a particular focus on the ocular surface condition. We plan to recruit 50 adults with ASD and 50 age-/sex-matched typically developing controls in this project, and perform visual function assessment.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.100 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Case-Control
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Any sex
Biological sex of participants that are eligible to enroll.Over 20 Years
Range of ages for which participants are eligible to join.Healthy volunteers allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
ASD group: Inclusion Criteria: 1. Having a clinical diagnosis of autism spectrum disorder 2. Aged over 20 years; able to read and sign an informed consent form. 3. Clear conscious and can follow the instruction of opening eyes and movement toward all direction. Exclusion Criteria: 1. Unable to cooperate with the examinations. 2. Younger than 20 years old. TD group: Inclusion Criteria: 1. Aged over 20 years; able to read and sign an informed consent form. 2. Clear conscious and can follow the instruction of opening eyes and movement toward all direction. Exclusion Criteria: 1. Unable to cooperate with the examinations. 2. Younger than 20 years old. 3. Having a clinical diagnosis of autism spectrum disorder
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Study Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
National Taiwan University Hospital
Taipei, TaiwanOpen National Taiwan University Hospital in Google Maps