Suspended

Mindreading in Adults With Autism Spectrum Disorder

What is being collected

Data Collection

Collected at a single point in time - Cross-sectional

Who is being recruted

Autism Spectrum Disorder+1

+ Mental Disorders

+ Child Development Disorders, Pervasive

From 20 to 50 Years

+4 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Case-Control

Comparing exposures between individuals with and without disease in order to identify potential risk factors.

Observational

Study Start: January 2019

See protocol details

Summary

Principal SponsorNational Taiwan University Hospital

Study ContactYi Ling Chien, M.D., Ph.D.

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: January 8, 2019

Actual date on which the first participant was enrolled.

Autism spectrum disorder (ASD) is a clinical syndrome characterized by mindreading deficits, or Theory of Mind deficits. The Reading the Mind in the Eyes task (abbreviated as the Eyes task) was developed to assess the mindreading deficits as a hallmark of social deficits of ASD. This study aims to investigate the ability of reading emotions by the Eyes task in adults with ASD, and examine the gazing pattern and frontal activation during the task. We plan to recruit 50 adults with ASD and 50 typically-developing adults. All the participants will complete clinical measures and the Eyes task. Eye-tracking and frontal activation (measured by functional near-infrared spectroscopy) will be examined during the Eyes task.

Official TitleMindreading in Adults With Autism Spectrum Disorder

NCT04010409

Principal SponsorNational Taiwan University Hospital

Study ContactYi Ling Chien, M.D., Ph.D.

Last updated: January 28, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

60 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Case-Control

These studies compare people who have a disease (cases) with those who don't (controls). The goal is to look back at previous exposures or risk factors to identify what might have contributed to the disease.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 20 to 50 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Autism Spectrum DisorderMental DisordersChild Development Disorders, PervasiveNeurodevelopmental Disorders

Criteria

2 inclusion criteria required to participate

Adult aged between 20 and 50 years who had a diagnosis of ASD based on DSM-5.

Had a full-scale IQ > 70 on WAIS-IV.

2 exclusion criteria prevent from participating

A history of major mental illness (e.g., bipolar affective disorder, schizophrenia) or neurological diseases.

Visual impairment and that would preclude participation.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

National Taiwan University Hospital

Taipei, TaiwanOpen National Taiwan University Hospital in Google Maps

SuspendedOne Study Center