Suspended

NEO-MENINGITISZekai Tahir Burak Women's Health Research and Education Hospital

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What is being collected

Data Collection

Collected from past medical records and data - Retrospective
Who is being recruted

Neuroinflammatory Diseases

+ Meningitis

+ Nervous System Diseases

+4 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: June 2019
See protocol details

Summary

Principal SponsorZekai Tahir Burak Women's Health Research and Education Hospital
Study ContactMehmet Yekta Oncel, M.D.More contacts
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: June 1, 2019

Actual date on which the first participant was enrolled.

Meningitis, defined as inflammation of the meninges caused by different pathogens, is a serious infection associated with high morbidity and mortality. It occurs more commonly in the neonatal period than in any other age group. Neonatal meningitis is a devastating infection that occurs more commonly in neonates than in any other age group, and is associated with significant morbidity and mortality. In this study, we aimed to evaluate epidemiology, treatment and prognosis of neonatal meningitis in a large-scale retrospective multicenter cohort study. The main objectives of this study were to assess the incidence, temporal trend, risk factors, causative organisms, and short term outcomes of neonatal meningitis in a large national cohort of newborn infants admitted to Turkey NICUs.

Official TitleZekai Tahir Burak Women's Health Research and Education Hospital
NCT04009551
Principal SponsorZekai Tahir Burak Women's Health Research and Education Hospital
Study ContactMehmet Yekta Oncel, M.D.More contacts
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

500 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Neuroinflammatory DiseasesMeningitisNervous System Diseases

Criteria

2 inclusion criteria required to participate
Subject has a positive cerebrospinal fluid culture/PCR of bacterial pathogen.
Subject has a positive blood culture of bacterial pathogen and counts of white blood cells in cerebrospinal fluid ≥20 /mm3.
2 exclusion criteria prevent from participating
Major congenital anomalies
Cultures positive for coagulase-negative staphylococci (CONS) were excluded as possible contaminants, if not clinically and laboratory compatible with meningitis.

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 5 locations

Recruiting

Zekai Tahir Burak Women's Health Research and Education Hospital

Ankara, Turkey (Türkiye)Open Zekai Tahir Burak Women's Health Research and Education Hospital in Google Maps
Recruiting

Bursa Yuksek Ihtisas Research and Education Hospital

Bursa, Turkey (Türkiye)
Recruiting

Gazi Yasargil Education Research Hospital

Diyarbakır, Turkey (Türkiye)
Recruiting

İstanbul Kanuni Sultan Süleyman Training and Research Hospital

Istanbul, Turkey (Türkiye)
Suspended5 Study Centers
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