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APACOPhysical Activity, Cancer and Cognitive Function Disorders : Effects of an Adapted Physical Activity Program on Impaired Cognitive Function in the Management of Cancer

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What is being tested

Adapted Physical Activity Program

Behavioral
Who is being recruted

Behavior

+ Motor Activity

Over 18 Years
+12 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Supportive Care Study

Interventional
Study Start: February 2019
See protocol details

Summary

Principal SponsorInstitut Cancerologie de l'Ouest
Study ContactBOIFFARD Florence, MDMore contacts
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: February 28, 2019

Actual date on which the first participant was enrolled.

1. Inclusion procedure and saving selection failures Participation in this study will be offered to patients during their care in day hospital (= inclusion visit). Any patient giving express consent to participation and meeting the criteria for inclusion and non-inclusion will then be included in the study. Each patient will then be identified by his or her initials as a patient number in the study, directly on the basis of collecting the data from the study. 2. Study progress for patients Data collection takes place over two different periods. Each period lasts 12 weeks. The Adapted Physical Activity (APA) program is 8 weeks old. The first period will run from mid-January to early April (first cohort) to collect data from the first patients in the experimental group. The second period will be from mid-February to the end of April. During this one, it will be necessary to collect the data of the last patients of the experimental group (second cohort) The first two weeks of each period (weeks 1 and 2, weeks 4 and 5) are dedicated to recruiting patients. During the pre-test session, carried out week 3 for the first cohort and weeks 6 for the second, the patients will carry out different tests and questionnaires: General Information Questionnaires, Education, MoCA (Montreal Cognitive Assessment), GPAQ (Global Physical Activity Questionnaire), Stroop test, test of MEM3 (Echelle Clinique de Mémoire), letter comparison test, HADS (Hospital and Anxiety Depression Scale), and the MFI (Multidimensional Fatigue Inventory). Patients should also wear an actimeter for one week from the day of recruitment. Patients then take part in a program of Adapted Physical Activity lasting 8 weeks, with 2 sessions per week. The sessions of this program are similar to the APA sessions already offered by sports therapy practitioners. This is an aerobic exercise session, with Nordic walking, and a combined session of muscle building and breathing-based exercises. In the post-test session, which was conducted week 12 for the first cohort and week 15 for the second, some questionnaires and tests are again administered: GPAQ, Stroop test, MEM3 test, letter comparison test, HADS and the MFI. Patients should also wear an actimeter the week before the day of the post-test. The forecast schedule may be slightly modified depending on unforeseen circumstances and constraints that may occur.

Official TitlePhysical Activity, Cancer and Cognitive Function Disorders : Effects of an Adapted Physical Activity Program on Impaired Cognitive Function in the Management of Cancer
NCT03949322
Principal SponsorInstitut Cancerologie de l'Ouest
Study ContactBOIFFARD Florence, MDMore contacts
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

26 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Supportive Care Study

These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

BehaviorMotor Activity

Criteria

6 inclusion criteria required to participate
Male or female> or = 18 years old

Any patient being treated for a cancerous condition and managed by adjuvant chemotherapy.

Any type of cancer

Beneficiary of a social protection scheme

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6 exclusion criteria prevent from participating
Protected subjects known as vulnerable (major under legal protection, adults unable to express their consent, subject admitted to a health and social institution).

Minor subjects

Pregnant women, likely to be pregnant or breastfeeding

Subjects with sensory disabilities affecting vision or hearing

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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Patients in the experimental group take part in a program of Adapted Physical Activity lasting 6 weeks, with 2 sessions per week.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Recruiting

Institut de Cancérologie de l'Ouest

Saint-Herblain, FranceOpen Institut de Cancérologie de l'Ouest in Google Maps
SuspendedOne Study Center