Completed

Effect of Red Light Rhinophototherapy on Nasal Patency in Patients With Allergic Rhinitis

0 criteria met from your profileSee at a glance how your profile meets each eligibility criteria.
What is being tested

Transverse Many Channels Laser Instrument

Device
Who is being recruted

Hypersensitivity+6

+ Hypersensitivity, Immediate

+ Immune System Diseases

Over 20 Years
+8 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Basic Science Study

Interventional
Study Start: March 2018
See protocol details

Summary

Principal SponsorTaichung Veterans General Hospital
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: March 2, 2018

Actual date on which the first participant was enrolled.

This study focuses on individuals experiencing moderate to severe symptoms of allergic rhinitis (AR), a condition characterized by nasal congestion, runny nose, itchy nose, or sneezing. The goal is to evaluate the effect of red light rhinophototherapy (RLRPT) on nasal patency in these patients. AR is diagnosed based on patient history, physical examination, and a specific IgE test against common allergens. Patients with a symptom score of 4 or more are enrolled, excluding those under 20, with severe nasal septum, rhinosinusitis, nasal polyposis, immunodeficiency, previous sinus surgery, recent upper respiratory tract infection, or oral corticosteroid use. Participants are randomly divided into two groups. The study group receives one session of RLRPT, delivered via a device called the Transverse Many Channels Laser Instrument. This involves placing light-emitting nasal probes into both nostrils for 15 minutes. After the treatment, patients rest for 30 minutes and then report on the severity of their symptoms and any changes. They also receive medical treatment involving an intranasal steroid and an oral antihistamine. Follow-up questions are asked 2 days later. The control group receives only the medical treatment, with follow-up questions asked 2 days later. The study measures nasal patency using active anterior rhinomanometry and acoustic rhinometry.

Official TitleEffect of Red Light Rhinophototherapy on Nasal Patency in Patients With Allergic Rhinitis
NCT03752645
Principal SponsorTaichung Veterans General Hospital
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

60 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.



Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 20 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

HypersensitivityHypersensitivity, ImmediateImmune System DiseasesNose DiseasesOtorhinolaryngologic DiseasesRespiratory HypersensitivityRespiratory Tract DiseasesRhinitisRhinitis, Allergic

Criteria

3 inclusion criteria required to participate
Patients experiencing moderate to severe symptoms of allergic rhinitis

Patients possessing at least one of the following symptoms: nasal congestion, runny nose, itchy nose, or sneezing

Patients whose physical examination showing clear rhinorrhea, nasal congestion, pale discoloration of the nasal mucosa, or red and watery eyes

5 exclusion criteria prevent from participating
Patients with age below 20 years old

Patients with severe nasal septum, rhinosinusitis and nasal polyposis

Patients who had a history of immunodeficiency or previous sinus surgery

Patients who suffered from an upper respiratory tract infection

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

One single intervention group is designated in this study

This study does not include a placebo group 

Treatment Groups

Group I

Experimental
Transverse Many Channels Laser Instrument

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Taichung Veterans General Hospital

Taichung, TaiwanOpen Taichung Veterans General Hospital in Google Maps
CompletedOne Study Center