Suspended
Effect of Adding Evening Primrose Oil to Misoprostol in Second Trimester Abortion
What is being tested
Evening primrose oil(EPO)
+ Placebo - Cap
Drug
Who is being recruted
Abortion, Spontaneous+2
+ Abortion, Missed
+ Urogenital Diseases
From 18 to 35 Years
+7 Eligibility Criteria
How is the trial designed
Treatment Study
Placebo-ControlledPhase 3
Interventional
Study Start: November 2018
Summary
Principal SponsorAin Shams University
Study ContactRadwa R Ali, MD
Last updated: January 27, 2026Sourced from a government-validated database.Claim as a partner
Study start date: November 1, 2018
Actual date on which the first participant was enrolled.efficacy of evening primrose oil in shortening the duration of induction in 2nd trimesteric missed abortion
Official TitleEffect of Adding Evening Primrose Oil to Misoprostol in Second Trimester Abortion
Principal SponsorAin Shams University
Study ContactRadwa R Ali, MD
Last updated: January 27, 2026Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Design Details
100 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
These studies test new ways to treat a disease, condition, or health issue. The goal is to see if a new drug, therapy, or approach works better or has fewer side effects than existing options.
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Female
Biological sex of participants that are eligible to enroll.From 18 to 35 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Abortion, SpontaneousAbortion, MissedUrogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsPregnancy Complications
Criteria
1 inclusion criteria required to participate
Primiparous women
6 exclusion criteria prevent from participating
Previous uterine incision( Cs, myomectomy,)
Contraindications to medical or surgical uterine evacuations (eg, hemodynamically unstable, coagulopathy)
Evidence of intra-uterine infection
Rupture of fetal membranes.
Show More Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.Treatment Groups
Study Objectives
2 intervention groups are designated in this study
50% chance of being blinded to the placebo group
Treatment Groups
Group I
Active ComparatorGroup II
PlaceboStudy Objectives
Primary Objectives
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has 1 location
Recruiting
AinShams university maternity hospital
Cairo, EgyptOpen AinShams university maternity hospital in Google MapsSuspendedOne Study Center