Suspended

Routine Cardiac Troponin Measurement in Elderly Surgery Patients

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Study Aim

The study aims to observe how routine cardiac troponin measurements affect surgical mortality rates within 30 days in elderly patients undergoing surgery.

What is being collected

Data Collection

Collected from today forward - Prospective
No DNA Sample
Who is being recruted

From 75 to 100 Years
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: August 2018
See protocol details

Summary

Principal SponsorUniversitair Ziekenhuis Brussel
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: August 23, 2018

Actual date on which the first participant was enrolled.

This study is focused on understanding how measuring a specific protein in the blood, known as cardiac troponin (hsTnT), can affect the outcomes for elderly patients undergoing major surgery. Cardiac troponin levels often rise due to heart muscle damage, but they can also elevate due to other issues like kidney problems or infections. High levels of this protein are commonly found in hospitalized patients and have been linked to a higher risk of death, even for those not having a heart attack. The study aims to find out if routinely checking troponin levels, along with assessing heart function, can help improve the health outcomes of elderly patients after surgery. Participants in the study will have their troponin levels measured before and after surgery. Additionally, a heart function test called transthoracic echocardiography will assess the heart's ability to relax and fill with blood, both before and after the surgical procedure. The main focus is on seeing if these measurements can predict or reduce the risk of death within 30 days after surgery. This information could be crucial in better understanding and potentially improving the care and recovery of elderly surgical patients.

Official TitleThe Impact of Routine Measurement of Cardiac Troponin (hsTnT) on Outcome in Elderly Patients Undergoing Major Surgery
NCT03605134
Principal SponsorUniversitair Ziekenhuis Brussel
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

63 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.


Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 75 to 100 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

Inclusion Criteria: * All patients ≥75 y undergoing elective and major surgery till we have collected an entire dataset of 100 patients. * Only those patients will be included who are planned for elective and major surgery. Exclusion Criteria: * Patients under the age of 75 * Intraoperative mortality * Eye surgery * Cardiac or thoracic surgery * Patients undergoing surgery which is not withheld as major surgery * For patients undergoing multiple surgeries for the same indication and during the same hospitalization, only the first surgery will be included

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Universitair Ziekenhuis Brussel

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SuspendedOne Study Center