Completed

Home-Based High-Intensity Interval Training for Obese Individuals with Elevated Cardiovascular Disease Risk

Study Aim

This study aims to evaluate your adherence and compliance to a home-based high-intensity interval training program, as well as observe the change in your aerobic fitness, if you are an obese individual with an elevated risk of cardiovascular disease.

What is being tested

Training mode

Behavioral

Who is being recruted

Body Weight+5

+ Nutrition Disorders

+ Nutritional and Metabolic Diseases

From 18 to 55 Years

+4 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Basic Science Study

Interventional

Study Start: March 2015

See protocol details

Summary

Principal SponsorLiverpool John Moores University

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: March 9, 2015

Actual date on which the first participant was enrolled.

This study focuses on a 12-week home-based exercise program designed for obese individuals who have an increased risk of cardiovascular disease. The goal is to create a workout plan that's suitable for people with low fitness and mobility levels, as current high-intensity interval training (HIT) programs often require special equipment and supervision. The study involves obese adults who have at least three additional risk factors for cardiovascular disease. The importance of this research lies in its potential to make exercise more accessible, thereby addressing a significant public health challenge. Participants in this study are divided into three groups. One group follows the home-based HIT program (Home-HIT), another group engages in a lab-supervised HIT program (Lab-HIT), and the third group performs moderate-intensity continuous training at home (Home-MICT). The Home-HIT group performs simple bodyweight exercises that don't require any equipment. The exercises are monitored using a heart rate monitor and a mobile app to ensure they're done correctly. The study measures changes in various health markers, such as aerobic fitness, insulin sensitivity, body composition, and heart health. It also assesses the participants' ability to stick to the exercise program and meet the target heart rates.

Official TitleEffects of a 12-Week Home-Based High-Intensity Interval Training Programme in Obese Individuals With Elevated Cardiovascular Disease Risk: A Pilot Study

NCT03557736

Principal SponsorLiverpool John Moores University

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

32 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Basic Science Study

Basic science studies help researchers understand how the body works or how a disease develops. They don't test treatments, but they build the foundation for future therapies.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Any sex

Biological sex of participants that are eligible to enroll.

From 18 to 55 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Body WeightNutrition DisordersNutritional and Metabolic DiseasesObesitySigns and SymptomsPathological Conditions, Signs and SymptomsOvernutritionOverweight

Criteria

2 inclusion criteria required to participate

obesity (BMI >30 kg/m2)

age 18-55

2 exclusion criteria prevent from participating

diagnosed CVD and other contraindications to participate in an exercise intervention

BMI <30 kg/m2

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Treatment Groups

Study Objectives

3 intervention groups are designated in this study

This study does not include a placebo group

Treatment Groups

Group I

Experimental

Home-based high-intensity interval training: participants performed 12 weeks of simple body weight exercises in a place of their own choosing 3x/week

Group II

Experimental

Home-based moderate-intensity interval training: participants performed 12 weeks of continuous exercise (running, swimming or cycling) in a place of their own choosing 3x/week

Group III

Experimental

Laboratory-based high-intensity interval training: participants performed supervised cycle exercise under laboratory conditions 3x/week for 12 weeks

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Liverpool John Moores University

Liverpool, United KingdomOpen Liverpool John Moores University in Google Maps

CompletedOne Study Center