Completed

OsTeaAssessing the Efficacy of Herbal Teas on Bone Health in an Osteopenic Population: OsTea

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What is being tested

Herbal Teas

Other
Who is being recruted

Bone Diseases+2

+ Bone Diseases, Metabolic

+ Metabolic Diseases

Over 18 Years
+13 Eligibility Criteria
See all eligibility criteria
How is the trial designed

Prevention Study

Placebo-Controlled
Interventional
Study Start: June 2018
See protocol details

Summary

Principal SponsorPaula Witt-Enderby
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: June 1, 2018

Actual date on which the first participant was enrolled.

The project goal is to identify if herbal teas consumed three times per day over a period of three months can improve these markers of bone health as well as improve quality of life (QOL) compared to women taking placebo by increasing osteoblast activity, decreasing osteoclast activity, increasing nocturnal melatonin levels and by decreasing C-reactive protein (CRP) and cortisol levels. Our central hypothesis is that these herbal teas will improve both objective and subjective measures of bone health in a population with osteopenia not taking this regimen by reducing osteoclast activity and increasing osteoblast activity and by reducing stress and anxiety.

Official TitleAssessing the Efficacy of Herbal Teas on Bone Health in an Osteopenic Population: OsTea
NCT03480126
Principal SponsorPaula Witt-Enderby
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

35 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Prevention Study

Prevention studies aim to stop a disease from developing. They often involve people at risk and test things like vaccines, lifestyle changes, or preventive medications.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Conditions
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 18 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Bone DiseasesBone Diseases, MetabolicMetabolic DiseasesMusculoskeletal DiseasesNutritional and Metabolic Diseases

Criteria

8 inclusion criteria required to participate
male or female with osteopenia (T-score between -1.0 and -2.5)
at least 18 years of age
must be willing to drink tea three times a day for 3 months
must also be willing to come to the study location on 4 occasions (baseline, end of month 1, end of month 2, and end of month 3),
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5 exclusion criteria prevent from participating
Women or men with osteoporosis
Women or men with osteopenia due to hyperparathyroidism, multiple myeloma, metastatic bone disease, chronic steroid use
Women or men who are on any bone therapies (i.e. bisphosphonates, selective estrogen receptor modulators, hormone therapy, teriparatide, and denosumab)
Women or men with chronic obstructive pulmonary disease (COPD)
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Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Treatment Groups
Study Objectives

4 intervention groups are designated in this study

25% chance of being blinded to the placebo group

Treatment Groups

Group I

Placebo
Placebo Tea should will be ingested 3 times per day for 3 months

Group II

Experimental
Experimental Herbal Tea A will be ingested 3 times per day for 3 months

Group III

Experimental
Experimental Herbal Tea B will be ingested 3 times per day for 3 months

Group IV

Experimental
Experimental Herbal Tea C will be ingested 3 times per day for 3 months

Study Objectives

Primary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

Duquesne University

Pittsburgh, United StatesOpen Duquesne University in Google Maps
CompletedOne Study Center