Aerobic Exercise Impact on Metabolic Responses and Abdominal Obesity in Women with Metabolic Syndrome
This study aims to evaluate the impact of aerobic exercise on metabolic responses and abdominal obesity in women with metabolic syndrome, by measuring changes in abdominal fat, epinephrine, free fatty acids, glycerol, noradrenaline, oxyntomodulin, and weight over a 12-week period and a 4-week detraining period.
Supervised treadmill group (%70 VO2 max) (group 1)
+ Supervised treadmill group (%50 VO2 max) (group 2)
+ ECE PEDO pedometer group (%50 VO2 max) (group 3)
Hyperinsulinism+3
+ Insulin Resistance
+ Metabolic Diseases
Treatment Study
Summary
Study start date: August 1, 2016
Actual date on which the first participant was enrolled.This study focuses on understanding the effects of aerobic exercise, performed at different intensities and durations, on metabolic and hormonal responses, as well as abdominal obesity in women diagnosed with metabolic syndrome. The research aims to provide insights into how varying exercise routines can impact these women's health. By exploring these effects, the study hopes to contribute to the development of more effective exercise strategies that can help manage metabolic syndrome and reduce abdominal obesity. Participants in this study are divided into three groups. The first group engages in high-intensity treadmill exercises, the second group in low-intensity treadmill exercises, and the third group in low-intensity walking with a pedometer. The progress of each participant is tracked over a 12-week period, followed by a 4-week detraining period. Various measurements, such as weight, BMI, waist circumference, blood sugar levels, and fat distribution, are taken at the beginning, end, and after the detraining period. Blood samples are also collected to evaluate changes in hormonal and metabolic parameters. The study's primary outcomes include changes in abdominal fat, hormone levels, and weight, which are expected to provide valuable insights into the benefits of different exercise intensities and durations.
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.60 patients to be enrolled
Total number of participants that the clinical trial aims to recruit.Treatment Study
Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Female
Biological sex of participants that are eligible to enroll.From 25 to 65 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
Criteria
Study Plan
Find out more about all the medication administered in this study, their detailed description and what they involve.3 intervention groups are designated in this study
This study does not include a placebo group
Treatment Groups
Group I
Active ComparatorGroup II
ExperimentalGroup III
ExperimentalStudy Objectives
Primary Objectives