Healthy Volunteer Recruitment and MRI & MEG Brain Scans for NIMH Studies

This study aims to create a list of healthy adult volunteers for research studies at the National Institute of Mental Health (NIMH) in Bethesda, Maryland. It also seeks to develop a set of normal brain MRI scans and MEG recordings linked to healthy volunteer characteristics. The study is important as it aims to maximize the scientific impact of data from volunteers by sharing it broadly with other researchers. The study is open to adult males and females in good health who are 18 to 70 years old. The study consists of two parts. The first part is an online screen where interested participants complete online forms to determine their eligibility for the second part, which is an in-person assessment at the NIH Clinical Center. There are also three optional procedures: an MRI brain scan, MEG recording, and electrocardiography (EKG) done at the NIH Clinical Center. Participants found ineligible due to significant or unstable medical or mental health conditions will be referred back to the community. Those eligible will undergo a clinical assessment that may include safety assessment, vital signs, history and physical, labs, cognitive tests, mental health surveys, and a structured psychiatric diagnostic interview. Some assessments may be conducted virtually. The primary outcome is a list of well-characterized healthy volunteers, while the secondary outcome is the upload of de-identified healthy volunteer characterization data to an open access data repository for secondary research purposes.