C-TRACTCatheter-Directed Therapy for Chronic Venous Thrombosis Relief

This study focuses on finding better ways to treat a condition called Deep Iliac Obstruction-Post Thrombotic Syndrome (DIO-PTS), which severely affects people's lives. Current treatments don't work well for everyone, and some options are risky and costly. The study looks at a new method called Endovenous Therapy (EVT), which uses procedures like stent placement and ablation to improve blood flow in the veins. The goal is to see if this method can be safely used more often to relieve symptoms and improve quality of life for those with DIO-PTS. The study aims to provide clear answers on whether EVT should become a standard treatment practice or not. In the study, 250 participants with DIO-PTS are divided into two groups: one receiving EVT and the other continuing with standard treatment alone. EVT involves procedures such as inserting a small mesh tube to keep the vein open and using heat to close off problematic veins. All participants will receive the usual care for DIO-PTS as well. The effectiveness of the treatments will be evaluated by measuring changes in the severity of the symptoms after six months. Participants’ health and progress will be monitored for either 6 or 24 months, depending on when they joined the study. This will help determine whether EVT is a valuable addition to current treatment options.