Suspended

Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial for Evaluation of Sperm Motility Improvement Effect of Fermented Ginseng(GINST)

What is being tested

fermented ginseng (GINST)

+ Placebo

Dietary Supplement

Who is being recruted

Urogenital Diseases+4

+ Genital Diseases

+ Genital Diseases, Male

From 18 to 60 Years

+10 Eligibility Criteria

See all eligibility criteria

How is the trial designed

Supportive Care Study

Placebo-Controlled

Interventional

Study Start: January 2017

See protocol details

Summary

Principal SponsorJae Hoon Lee

Study ContactJae Hoon LEE, M.D.More contacts

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Study start date: January 26, 2017

Actual date on which the first participant was enrolled.

This multicenter, randomized, double-blind, placebo-controlled clinical trial was aimed to evaluate of sperm motility improvement effect of fermented ginseng(GINST). Experimental arm and control arm were randomly assigned among the volunteers who met the inclusion criteria: men between the ages of 18 and 60 who had sperm motility of less than 32%. To experimental arm, capsules including 160mg of fermented ginseng(GINST) ingredients will be provided for 12 weeks. To control arm, capsules of the same shape and weight as GINST capsules will be provided. These capsules are made of a cellulose component. Primary outcome is sperm motility. Secondary outcome are <Brief Male Sexual Function Inventory> , <Fatigue Severity Scale>, and <the Short Form (36) Health Survey> measured at baseline and end of the trial.

Official TitleMulticenter, Randomized, Double-blind, Placebo-controlled Clinical Trial for Evaluation of Sperm Motility Improvement Effect of Fermented Ginseng(GINST)

NCT03183999

Principal SponsorJae Hoon Lee

Study ContactJae Hoon LEE, M.D.More contacts

Last updated: January 27, 2026

Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.

Design Details

60 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Supportive Care Study

These studies explore ways to improve comfort and daily life for people living with a condition. They may focus on easing symptoms, reducing treatment side effects, or supporting overall well-being.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.

Conditions

Criteria

Male

Biological sex of participants that are eligible to enroll.

From 18 to 60 Years

Range of ages for which participants are eligible to join.

Healthy volunteers allowed

If individuals who are healthy and do not have the condition being studied can participate.

Conditions

Pathology

Urogenital DiseasesGenital DiseasesGenital Diseases, MaleInfertilityInfertility, MaleMale Urogenital DiseasesAsthenozoospermia

Criteria

2 inclusion criteria required to participate

Male between 18 and 60 years old

Men who have agreed to participate in this trial before the start of the study and who have written an informed consent

8 exclusion criteria prevent from participating

Those who are diagnosed and treated for hypertension (systolic blood pressure> 140mmHg and diastolic blood pressure> 90mmHg)

Patients with a history of chemotherapy for malignant tumors

Patients with a history of taking testosterone or antiandrogens within 1 month

BMI> 30 or BMI <18

Show More Criteria

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.

Treatment Groups

Study Objectives

2 intervention groups are designated in this study

50% chance of being blinded to the placebo group

Treatment Groups

Group I

Experimental

Experimental group was randomly assigned among the volunteers who met the inclusion criteria: men between the ages of 18 and 60 who had sperm motility of less than 32%. Fermented ginseng (GINST) was supplied.

Group II

Placebo

Control group was randomly assigned among the volunteers who met the inclusion criteria: men between the ages of 18 and 60 who had sperm motility of less than 32%. Placebo was supplied.

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 3 locations

Recruiting

Wonju Severance Christian Hospital

Wŏnju, South KoreaOpen Wonju Severance Christian Hospital in Google Maps

Recruiting

Gil Hospital

Incheon, South Korea

Recruiting

Severance Hospital

Seoul, South Korea

Suspended3 Study Centers