Tesamorelin for Peripheral Nerve Injury Recovery

This clinical trial is exploring the potential benefits of a drug called tesamorelin for people who have suffered a peripheral nerve injury, specifically to the ulnar nerve, which can affect hand and arm function. Tesamorelin helps increase the production of growth hormone, which has shown promise in animal studies for aiding nerve repair and improving recovery. The main aim is to see if tesamorelin can help improve outcomes for patients, such as better strength and functionality in the affected area. This study is important because nerve injuries can lead to lasting difficulties and finding effective treatments can significantly enhance recovery and quality of life. In this study, 36 participants with repaired ulnar nerve injuries are involved. Half of them will receive tesamorelin, while the other half will not receive any additional treatment, allowing researchers to compare results. All participants will attend 12 monthly follow-up visits for various assessments, including clinical exams, electrical tests of nerve function, and answering questionnaires about their recovery. The effectiveness of the treatment is measured using tests like the "3-point chuck pinch test," which evaluates pinch strength. The study will ensure unbiased results by keeping the evaluators unaware of who received the drug. The trial will last for approximately four years, providing comprehensive data on the potential benefits of tesamorelin.