Suspended
Expanded Access to ABT-414
What is being tested
Data Collection
Who is eligible
Astrocytoma+10
+ Disease
+ Glioblastoma
Over 18 Years
+4 Eligibility Criteria
How is it accessible
Suspended
Available upon a request by a licensed MDExpanded Access
Summary
Principal SponsorAbbVie
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
This is an expanded access program (EAP) for eligible participants. This program is designed to provide access to ABT-414 prior to approval by the local regulatory agency. Availability will depend on territory eligibility. Participating sites will be added as they apply for and are approved for the EAP. A medical doctor must decide whether the potential benefit outweighs the risk of receiving an investigational therapy based on the individual patient's medical history and program eligibility criteria.
Official TitleExpanded Access to ABT-414
Principal SponsorAbbVie
Last updated: January 27, 2026
Sourced from a government-validated database.Claim as a partner
Protocol
This section provides details of the study plan, including how the study is designed and what the study is measuring.Eligibility
Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.Conditions
Criteria
Any sex
Biological sex of participants that are eligible to enroll.Over 18 Years
Range of ages for which participants are eligible to join.Healthy volunteers not allowed
If individuals who are healthy and do not have the condition being studied can participate.Conditions
Pathology
AstrocytomaDiseaseGlioblastomaGliomaNeoplasmsNeoplasms by Histologic TypeNeoplasms, Germ Cell and EmbryonalNeoplasms, Glandular and EpithelialNeoplasms, Nerve TissuePathologic ProcessesPathological Conditions, Signs and SymptomsNeuroectodermal TumorsNeoplasms, Neuroepithelial
Criteria
4 inclusion criteria required to participate
Participant must have epidermal growth factor receptor (EGFR) amplification or EGFRvIII mutation.
Health Care Provider (HCP) must have prior clinical trial experience with ABT-414.
The participant must not be eligible for an ABT-414 clinical trial.
Pediatric participants may be evaluated on a case by case basis.
Study Centers
These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.This study has no location dataSave this study to your profile to know when the location data is available.
SuspendedNo study centers