Suspended

SCOPAHAdvanced Heart Failure: Patient Preferences, Healthcare Access and Quality of Life Study

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Study Aim

This observational study aims to assess various aspects of life in patients with advanced heart failure, including changes in daily activities, distress levels, overall quality of life, cognitive status, treatment compliance, and perceived quality of care, as well as total healthcare expenditures in the last year of life.

What is being collected

Data Collection

Collected from today forward - Prospective
Who is being recruted

Over 21 Years
See all eligibility criteria
How is the trial designed

Cohort

Tracking disease incidence in order to identify risk factors and understand disease progression over time.
Observational
Study Start: July 2017
See protocol details

Summary

Principal SponsorDuke-NUS Graduate Medical School
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Study start date: July 24, 2017

Actual date on which the first participant was enrolled.

This study focuses on patients in Singapore who have advanced heart failure, specifically those in the New York Heart Association class III and IV. Its main goal is to understand the relationship between patient preferences, healthcare access, utilization, costs, and quality of life. By enrolling 300 patients and surveying them every 4 months for two years or until they pass away, the study aims to identify strategies to improve the end-of-life experience. Recognizing the significant role of family in medical decision making in Asia, the study also involves caregivers to evaluate their role in treatment decisions. During the study, various aspects of the patients' condition will be assessed. This includes changes in daily activities, distress levels, overall quality of life, and cognitive status. The study will also monitor the patients' compliance with treatment regimens and self-care behaviors. Patients' perceived quality of care during the last year of life will be evaluated, and the total healthcare expenditure during this period will be calculated through analysis of medical bills.

Official TitleSingapore Cohort of Patients with Advanced Heart Failure
NCT03089034
Principal SponsorDuke-NUS Graduate Medical School
Last updated: January 28, 2026
Sourced from a government-validated database.Claim as a partner

Protocol

This section provides details of the study plan, including how the study is designed and what the study is measuring.
Design Details

300 patients to be enrolled

Total number of participants that the clinical trial aims to recruit.

Cohort

These studies follow a group of individuals with common characteristics (such as a condition or birth year) over a specific period to study health outcomes or exposures.

Eligibility

Researchers look for people who fit a certain description, called eligibility criteria: person's general health condition or prior treatments.
Criteria

Any sex

Biological sex of participants that are eligible to enroll.

Over 21 Years

Range of ages for which participants are eligible to join.

Healthy volunteers not allowed

If individuals who are healthy and do not have the condition being studied can participate.

Criteria

Inclusion Criteria (patients): * Age ≥ 21 years old * Singaporean or Singapore Permanent Resident * Diagnosis of advanced Congestive Heart Failure (New York Heart Association Class III and IV). * Intact cognition (of patients ≥60 years of age) as determined by the Montreal Cognitive Assessment. If patient fails the cognitive test, he/she continues to be eligible for the study although self-reported data will no longer be collected. The primary informal caregiver of the patient will be approached for providing consent on behalf of the patient, to allow access to review of patient's medical and billing records The inclusion criteria (primary informal caregivers) * Age ≥ 21 years old * Main person or one of the main providing care to the patient (e.g. accompanying patient for doctor's visits, helping the patient with day to day activities) * Main person or one of the main ensuring provision of care (e.g. supervision of foreign domestic worker so that the patient is looked after) * Main person or one of the main involved in making decisions regarding treatment the patient receives * Patient they are caring for is enrolled in the study The inclusion criteria (physicians) • Patients they are treating are enrolled in the study Exclusion Criteria (patients): * Patients who are not Singaporeans or Singapore Permanent Residents * Patients who are ≤21 years of age * Patients with psychiatric or cognitive disorders Exclusion criteria (caregivers) • Foreign domestic workers/ maids will be excluded from this study

Study Plan

Find out more about all the medication administered in this study, their detailed description and what they involve.
Study Objectives

Study Objectives

Primary Objectives

Secondary Objectives

Study Centers

These are the hospitals, clinics, or research facilities where the trial is being conducted. You can find the location closest to you and its status.

This study has 1 location

Suspended

National Heart Centre Singapore

Singapore, SingaporeOpen National Heart Centre Singapore in Google Maps
SuspendedOne Study Center